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BMC Developmental Biology


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  1. Content type: Research article

    The pituitary gland is a highly vascularized tissue that requires coordinated interactions between the neural ectoderm, oral ectoderm, and head mesenchyme during development for proper physiological function. ...

    Authors: Shannon W. Davis, Amanda H. Mortensen, Jessica L. Keisler, Amanda L. Zacharias, Philip J. Gage, Ken-ichi Yamamura and Sally A. Camper

    Citation: BMC Developmental Biology 2016 16:16

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  2. Content type: Research article

    Wnt5a and Mrfzb1 genes are involved in the regulation of tooth size, and their expression levels are similar to that of Bmp7 during morphogenesis, including during the cap and early be...

    Authors: Kazuyuki Saito, Katsu Takahashi, Masakazu Asahara, Honoka Kiso, Yumiko Togo, Hiroko Tsukamoto, Boyen Huang, Manabu Sugai, Akira Shimizu, Masaharu Motokawa, Harold C. Slavkin and Kazuhisa Bessho

    Citation: BMC Developmental Biology 2016 16:14

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  3. Content type: Research article

    During early development of the nervous system, gene expression patterns are known to vary widely depending on the specific developmental trajectories of different structures. Observable changes in gene expres...

    Authors: Jimena Monzón-Sandoval, Atahualpa Castillo-Morales, Araxi O. Urrutia and Humberto Gutierrez

    Citation: BMC Developmental Biology 2016 16:13

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  4. Content type: Research article

    The contribution of programmed cell death (PCD) to muscle wasting disorders remains a matter of debate. Drosophila melanogaster metamorphosis offers the opportunity to study muscle cell death in the context of de...

    Authors: Yadav Kuleesha, Wee Choo Puah and Martin Wasser

    Citation: BMC Developmental Biology 2016 16:12

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  5. Content type: Research article

    We previously reported that the pluripotent stem cells can differentiate into cardiomyocytes (CMs) by co-culture with neonatal CMs (NCMs) in vitro. However, the involving mechanism is not clear.

    Authors: Dongbo Ou, Qi Wang, Yanjin Huang, Di Zeng, Ting Wei, Lu Ding, Xiaoli Li, Qiangsun Zheng and Yan Jin

    Citation: BMC Developmental Biology 2016 16:11

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  6. Content type: Research article

    Detailed descriptions of the early development of parasitic nematodes are seldom available. The embryonic development of the plant-parasitic nematode Meloidogyne incognita was studied, focusing on the early event...

    Authors: Alejandro Calderón-Urrea, Bartel Vanholme, Sandra Vangestel, Saben M. Kane, Abdellatif Bahaji, Khavong Pha, Miguel Garcia, Alyssa Snider and Godelieve Gheysen

    Citation: BMC Developmental Biology 2016 16:10

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  7. Content type: Research article

    Mollusca is the second largest phylum in nature. The shell of molluscs is a remarkable example of a natural composite biomaterial. Biomineralization and how it affects mollusks is a popular research topic. The...

    Authors: Mi Zhao, Yu Shi, Maoxian He, Xiande Huang and Qi Wang

    Citation: BMC Developmental Biology 2016 16:9

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  8. Content type: Research article

    It has been suggested that the ectopic expression of PDX1, a dominant pancreatic transcription factor, plays a critical role in the developmental programming of the pancreas even from cells of unrelated tissue...

    Authors: Shruti Balaji, Yu Zhou, Anasuya Ganguly, Emmanuel C. Opara and Shay Soker

    Citation: BMC Developmental Biology 2016 16:8

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  9. Content type: Research article

    Akt (PKB) is a serine threonine protein kinase downstream of the phosphoinositide 3-kinase (PI3K) pathway. In mammals, Akt is ubiquitously expressed and is associated with regulation of cellular proliferation,...

    Authors: T. Harshani Peiris, Daniel Ramirez, Paul G. Barghouth and Néstor J. Oviedo

    Citation: BMC Developmental Biology 2016 16:7

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  10. Content type: Methodology article

    Time-lapse imaging has proven highly valuable for studying development, yielding data of much finer resolution than traditional “still-shot” studies and allowing direct examination of tissue and cell dynamics....

    Authors: Eduardo E. Zattara, Kate W. Turlington and Alexandra E. Bely

    Citation: BMC Developmental Biology 2016 16:6

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  11. Content type: Research article

    Microenvironments called niches maintain resident stem cell populations by balancing self-renewal with differentiation, but the genetic regulation of this process is unclear. The niche of the Drosophila testis...

    Authors: Amanda J. Monahan and Michelle Starz-Gaiano

    Citation: BMC Developmental Biology 2016 16:5

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  12. Content type: Research article

    The Hedgehog (Hh) signaling pathway, acting through three homologous transcription factors (GLI1, GLI2, GLI3) in vertebrates, plays multiple roles in embryonic organ development and adult tissue homeostasis. A...

    Authors: Katherine Gurdziel, Kyle R. Vogt, Gary Schneider, Neil Richards and Deborah L. Gumucio

    Citation: BMC Developmental Biology 2016 16:4

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  13. Content type: Methodology article

    The correct evaluation of mineralization is fundamental for the study of skeletal development, maintenance, and regeneration. Current methods to visualize mineralized tissue in zebrafish rely on: 1) fixed spec...

    Authors: A. Bensimon-Brito, J. Cardeira, G. Dionísio, A. Huysseune, M. L. Cancela and P. E. Witten

    Citation: BMC Developmental Biology 2016 16:2

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  14. Content type: Research article

    Bone morphogenetic proteins regulate multiple processes in embryonic development, including early dorso-ventral patterning and neural crest development. BMPs activate heteromeric receptor complexes consisting ...

    Authors: Carolin Schille, Jens Heller and Alexandra Schambony

    Citation: BMC Developmental Biology 2016 16:1

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  15. Content type: Research article

    It has been found that microRNAs (miRNAs) play important roles in the regulation of tooth development, and most likely increase the complexity of the genetic network, thus lead to greater complexity of teeth. ...

    Authors: Ang Li, Ye Li, Tieli Song, Fu Wang, Dayong Liu, Zhipeng Fan, San Cheng, Chunmei Zhang, Jinsong Wang, Junqi He and Songlin Wang

    Citation: BMC Developmental Biology 2015 15:51

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  16. Content type: Methodology article

    The vertebrate heart consists of three cell layers: the innermost endothelium, the contractile myocardium and the outermost epicardium. The epicardium is vital for heart development and function, and forms fro...

    Authors: Monica S. Yue, Jessica S. Plavicki, Xin-yi Li, Richard E. Peterson and Warren Heideman

    Citation: BMC Developmental Biology 2015 15:50

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  17. Content type: Research article

    This study describes the generation and analysis of the transcriptional profile of bovine inner cell mass (ICM) and trophectoderm (TE), obtained from in vivo developed embryos by using a bovine-embryo specific...

    Authors: S. M. Hosseini, I. Dufort, J. Caballero, F. Moulavi, H. R. Ghanaei and M. A. Sirard

    Citation: BMC Developmental Biology 2015 15:49

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  18. Content type: Research article

    Salamanders regenerate their tails after amputation anywhere along their length. How the system faithfully reconstitutes the original number of segments and length is not yet known.

    Authors: Carr D. Vincent, Fabian Rost, Wouter Masselink, Lutz Brusch and Elly M. Tanaka

    Citation: BMC Developmental Biology 2015 15:48

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  19. Content type: Research article

    Biliary atresia (BA) is a human infant disease with inflammatory fibrous obstructions in the bile ducts and is the most common cause for pediatric liver transplantation. In contrast, the sea lamprey undergoes ...

    Authors: Yu-Wen Chung-Davidson, Chu-Yin Yeh, Ugo Bussy, Ke Li, Peter J. Davidson, Kaben G. Nanlohy, C. Titus Brown, Steven Whyard and Weiming Li

    Citation: BMC Developmental Biology 2015 15:47

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  20. Content type: Methodology article

    Super-resolution fluorescence microscopy performed via 3D structured illumination microscopy (3D-SIM) is well established on flat, adherent cells. However, blastomeres of mammalian embryos are non-adherent, ro...

    Authors: Jens Popken, Maik Dahlhoff, Tuna Guengoer, Eckhard Wolf and Valeri Zakhartchenko

    Citation: BMC Developmental Biology 2015 15:46

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  21. Content type: Research article

    The endogenous ability to dedifferentiate, re-pattern, and re-differentiate adult cells to repair or replace damaged or missing structures is exclusive to only a few tetrapod species. The Mexican axolotl is on...

    Authors: Catherine D. McCusker, Antony Athippozhy, Carlos Diaz-Castillo, Charless Fowlkes, David M. Gardiner and S. Randal Voss

    Citation: BMC Developmental Biology 2015 15:45

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  22. Content type: Research article

    Acute kidney injury in mammals, which is caused by cardiovascular diseases or the administration of antibiotics with nephrotoxic side-effects is a life-threatening disease, since loss of nephrons is irreversib...

    Authors: Beate Hoppe, Stefan Pietsch, Martin Franke, Sven Engel, Marco Groth, Matthias Platzer and Christoph Englert

    Citation: BMC Developmental Biology 2015 15:43

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  23. Content type: Research article

    The investigation of skeletal muscle development is of importance in stock farming and biomedicine. It is still ambiguous that whether animals are born with the full set of skeletal muscle fibers or if the num...

    Authors: Mingsen Li, Xingyu Zhou, Yaosheng Chen, Yaping Nie, Huaxing Huang, Hu Chen and Delin Mo

    Citation: BMC Developmental Biology 2015 15:42

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2016 Journal Metrics

  • Citation Impact
    2.280 - 2-year Impact Factor
    2.616 - 5-year Impact Factor
    0.708 - Source Normalized Impact per Paper (SNIP)
    1.353 - SCImago Journal Rank (SJR)

    1092.5 Usage Factor

    Social Media Impact
    43 Mentions