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Page 5 of 20

  1. Tissue injury has been employed to study diverse biological processes such as regeneration and inflammation. In addition to physical or surgical based methods for tissue injury, current protocols for localized...

    Authors: José Moya-Díaz, Oscar A Peña, Mario Sánchez, Daniela A Ureta, Nicole G Reynaert, Consuelo Anguita-Salinas, Gonzalo Marín and Miguel L Allende

    Citation: BMC Developmental Biology 2014 14:7

    Content type: Methodology article

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  2. After completion of embryogenesis, many organisms experience an additional obligatory developmental transition to attain a substantially different juvenile or adult form. During anuran metamorphosis, the aquat...

    Authors: Taka-Aki Ichu, Jun Han, Christoph H Borchers, Mary Lesperance and Caren C Helbing

    Citation: BMC Developmental Biology 2014 14:5

    Content type: Research article

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  3. The injection of Neb-colloostatin into T. molitor females causes gonadoinhibitory effects on ovarian development. This peptide inhibits intercellular space formation (patency) in follicular epithelium and results...

    Authors: Elżbieta Czarniewska, Grzegorz Rosiński, Elżbieta Gabała and Mariola Kuczer

    Citation: BMC Developmental Biology 2014 14:4

    Content type: Research article

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  4. LIM domain binding protein 1 (LDB1) is a transcriptional co-factor, which interacts with multiple transcription factors and other proteins containing LIM domains. Complete inactivation of Ldb1 in mice resulted in...

    Authors: Asma Almaidhan, Jeffry Cesario, Andre Landin Malt, Yangu Zhao, Neeti Sharma, Veronica Choi and Juhee Jeong

    Citation: BMC Developmental Biology 2014 14:3

    Content type: Research article

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  5. The editors of BMC Developmental Biology would like to thank all our reviewers who have contributed to the journal in Volume 13 (2013).

    Authors: Philippa K Harris

    Citation: BMC Developmental Biology 2014 14:1

    Content type: Reviewer acknowledgement

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  6. Krüppel-like Factor 2 (KLF2) plays an important role in vessel maturation during embryonic development. In adult mice, KLF2 regulates expression of the tight junction protein occludin, which may allow KLF2 to ...

    Authors: Aditi R Chiplunkar, Benjamin C Curtis, Gabriel L Eades, Megan S Kane, Sean J Fox, Jack L Haar and Joyce A Lloyd

    Citation: BMC Developmental Biology 2013 13:40

    Content type: Research article

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  7. Disabled-2 (Dab2) is an endocytic adaptor protein involved in clathrin-mediated endocytosis and cargo trafficking. Since its expression is lost in several cancer types, Dab2 has been suggested to be a tumor su...

    Authors: Robert Moore, Kathy Qi Cai, Wensi Tao, Elizabeth R Smith and Xiang-Xi Xu

    Citation: BMC Developmental Biology 2013 13:39

    Content type: Research article

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  8. It has been proven that c-kit is crucial for proliferation, migration, survival and maturation of spermatogenic cells. A periodic expression of c-kit is observed from primordial germ cells (PGCs) to spermatogenet...

    Authors: Lei Zhang, Jiangjing Tang, Christopher J Haines, Huai Feng, Liangxue Lai, Xiaoming Teng and Yibing Han

    Citation: BMC Developmental Biology 2013 13:38

    Content type: Research article

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  9. The myotome is the primitive skeletal muscle that forms within the embryonic metameric body wall. It can be subdivided into an epaxial and hypaxial domain. It has been shown that the formation of the epaxial m...

    Authors: Qin Pu, Aisha Abduelmula, Maryna Masyuk, Carsten Theiss, Dieter Schwandulla, Michael Hans, Ketan Patel, Beate Brand-Saberi and Ruijin Huang

    Citation: BMC Developmental Biology 2013 13:37

    Content type: Research article

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    The Erratum to this article has been published in BMC Developmental Biology 2013 13:41

  10. Members of the vertebrate Numb family of cell fate determinants serve multiple functions throughout early embryogenesis, including an essential role in the development of the nervous system. The Numb proteins ...

    Authors: Frank Nieber, Marie Hedderich, Olaf Jahn, Tomas Pieler and Kristine A Henningfeld

    Citation: BMC Developmental Biology 2013 13:36

    Content type: Research article

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  11. Diacylglycerol kinase (DGK) is a key enzyme that regulates diacylglycerol (DG) turnover and is involved in a variety of physiological functions. The isoform DGKθ has a unique domain structure and is the sole m...

    Authors: Shuji Ueda, Becky Tu-Sekine, Minoru Yamanoue, Daniel M Raben and Yasuhito Shirai

    Citation: BMC Developmental Biology 2013 13:35

    Content type: Research article

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  12. Human amniotic fluid cells (hAFCs) may differentiate into multiple cell lineages and thus have a great potential to become a donor cell source for regenerative medicine. The ability of hAFCs to differentiate i...

    Authors: Dongmei Lai, Fangyuan Wang, Yifei Chen, Li Wang, Yanlin Wang and Weiwei Cheng

    Citation: BMC Developmental Biology 2013 13:34

    Content type: Research article

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  13. Velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS) is caused by a 1.5-3 Mb microdeletion of chromosome 22q11.2, frequently referred to as 22q11.2 deletion syndrome (22q11DS). This region includes TBX1, a T-...

    Authors: Laina Freyer, Sonja Nowotschin, Melinda K Pirity, Antonio Baldini and Bernice E Morrow

    Citation: BMC Developmental Biology 2013 13:33

    Content type: Methodology article

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  14. Preimplantation bovine development is emerging as an attractive experimental model, yet little is known about the mechanisms underlying trophoblast (TE)/inner cell mass (ICM) segregation in cattle. To gain an ...

    Authors: Zofia E Madeja, Jaroslaw Sosnowski, Kamila Hryniewicz, Ewelina Warzych, Piotr Pawlak, Natalia Rozwadowska, Berenika Plusa and Dorota Lechniak

    Citation: BMC Developmental Biology 2013 13:32

    Content type: Research article

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  15. The reiterated architecture of cranial motor neurons aligns with the segmented structure of the embryonic vertebrate hindbrain. Anterior-posterior identity of cranial motor neurons depends, in part, on retinoi...

    Authors: Danna L Drummond, Caroline S Cheng, Lyndsay G Selland, Jennifer C Hocking, Lisa B Prichard and Andrew J Waskiewicz

    Citation: BMC Developmental Biology 2013 13:31

    Content type: Research article

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  16. Aedes aegypti is the most important global vector of dengue virus infection in humans. Availability of the draft genome sequence of this mosquito provides unique opportunities to study different aspects of its bi...

    Authors: Brent W Harker, Susanta K Behura, Becky S deBruyn, Diane D Lovin, Akio Mori, Jeanne Romero-Severson and David W Severson

    Citation: BMC Developmental Biology 2013 13:29

    Content type: Research article

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  17. Ecdysone triggers transcriptional changes via the ecdysone receptor (EcR) to coordinate developmental programs of apoptosis, cell cycle and differentiation. Data suggests EcR affects cell cycle gene expression...

    Authors: Naomi C Mitchell, Jane I Lin, Olga Zaytseva, Nicola Cranna, Amanda Lee and Leonie M Quinn

    Citation: BMC Developmental Biology 2013 13:28

    Content type: Research article

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  18. Hox genes, with their similar roles in animals as evolutionarily distant as humans and flies, have fascinated biologists since their discovery nearly 30 years ago. During the last two decades, reports on Hox gene...

    Authors: Juan Pascual-Anaya, Salvatore D’Aniello, Shigeru Kuratani and Jordi Garcia-Fernàndez

    Citation: BMC Developmental Biology 2013 13:26

    Content type: Review

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  19. The Drosophila larval head is evolutionarily derived at the genetic and morphological level. In the beetle Tribolium castaneum, development of the larval head more closely resembles the ancestral arthropod condit...

    Authors: Andrew D Peel, Julia Schanda, Daniela Grossmann, Frank Ruge, Georg Oberhofer, Anna F Gilles, Johannes B Schinko, Martin Klingler and Gregor Bucher

    Citation: BMC Developmental Biology 2013 13:25

    Content type: Research article

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  20. The explanted, developing rodent retina provides an efficient and accessible preparation for use in gene transfer and pharmacological experimentation. Many of the features of normal development are retained in...

    Authors: Philip EB Nickerson, Kara M Ronellenfitch, Nicklaus F Csuzdi, Jamie D Boyd, Perry L Howard, Kerry R Delaney and Robert L Chow

    Citation: BMC Developmental Biology 2013 13:24

    Content type: Methodology article

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  21. The vertebrate craniofacial skeleton may exhibit anatomical complexity and diversity, but its genesis and evolution can be understood through careful dissection of developmental programs at cellular resolution...

    Authors: B Frank Eames, April DeLaurier, Bonnie Ullmann, Tyler R Huycke, James T Nichols, John Dowd, Marcie McFadden, Mark M Sasaki and Charles B Kimmel

    Citation: BMC Developmental Biology 2013 13:23

    Content type: Database

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  22. Toxic substances like heavy metals can inhibit and disrupt the normal embryonic development of organisms. Exposure to platinum during embryogenesis has been shown to lead to a “one fell swoop” internalization ...

    Authors: Leonie Marschner, Julian Staniek, Silke Schuster, Rita Triebskorn and Heinz-R Köhler

    Citation: BMC Developmental Biology 2013 13:22

    Content type: Research article

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  23. Extracellular leucine-rich repeat (eLRR) proteins are a highly diverse superfamily of membrane-associated or secreted proteins. In the membrane-associated eLRR proteins, the leucine-rich repeat motifs interact...

    Authors: Chris R Gissendanner and Tram Do Kelley

    Citation: BMC Developmental Biology 2013 13:21

    Content type: Research article

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  24. The purpose of the study was an evaluation of fetal hip joint morphology during the second and the third trimester of pregnancy. Serial sections were performed on 23 cadaver infants.

    Authors: Adrian Masłoń, Marcin Sibiński, Mirosław Topol, Karol Krajewski and Andrzej Grzegorzewski

    Citation: BMC Developmental Biology 2013 13:19

    Content type: Research article

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  25. Phosphatase of regenerating liver (PRL) family is classified as class IVa of protein tyrosine phosphatase (PTP4A) that removes phosphate groups from phosphorylated tyrosine residues on proteins. PRL phosphatas...

    Authors: Ming-Der Lin, Hsun-Tzu Lee, Szu-Chieh Wang, Han-Ru Li, Hsin-Lun Hsien, Kai-Wen Cheng, Yu-Di Chang, Min-Lang Huang, Jr-Kai Yu and Yau-Hung Chen

    Citation: BMC Developmental Biology 2013 13:18

    Content type: Research article

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  26. Molecular studies of appendage regeneration have been hindered by the lack of a stable and efficient means of transferring exogenous genes. We therefore sought an efficient integrating virus system that could ...

    Authors: Shahryar Khattak, Tatiana Sandoval-Guzmán, Nicole Stanke, Stephanie Protze, Elly M Tanaka and Dirk Lindemann

    Citation: BMC Developmental Biology 2013 13:17

    Content type: Methodology article

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  27. Protein kinase C epsilon (PKCϵ) belongs to the novel PKC subfamily, which consists of diacylglycerol dependent- and calcium independent-PKCs. Previous studies have shown that PKCϵ is important in different con...

    Authors: Sergio Carracedo, Ursula Braun and Michael Leitges

    Citation: BMC Developmental Biology 2013 13:16

    Content type: Research article

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  28. Live imaging provides an essential methodology for understanding complex and dynamic cell behaviors and their underlying molecular mechanisms. Genetically-encoded reporter expressing mouse strains are an impor...

    Authors: Sonja Nowotschin, Panagiotis Xenopoulos, Nadine Schrode and Anna-Katerina Hadjantonakis

    Citation: BMC Developmental Biology 2013 13:15

    Content type: Methodology article

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  29. The phoronid larva, which is called the actinotrocha, is one of the most remarkable planktotrophic larval types among marine invertebrates. Actinotrochs live in plankton for relatively long periods and undergo...

    Authors: Elena N Temereva and Eugeni B Tsitrin

    Citation: BMC Developmental Biology 2013 13:14

    Content type: Research article

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  30. MicroRNAs play important roles in regulating biological processes, including organ morphogenesis and maturation. However, little is known about specific pathways regulated by miRNA during lung development. Bet...

    Authors: Sana Mujahid, Tanya Logvinenko, MaryAnn V Volpe and Heber C Nielsen

    Citation: BMC Developmental Biology 2013 13:13

    Content type: Research article

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  31. Transcription factors from the MADS-box family play a relevant role in cell differentiation and development and include the animal SRF (serum response factor) and MEF2 (myocyte enhancer factor 2) proteins. The...

    Authors: María Galardi-Castilla, Irene Fernandez-Aguado, Teresa Suarez and Leandro Sastre

    Citation: BMC Developmental Biology 2013 13:12

    Content type: Research article

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  32. Our current knowledge on tooth development derives primarily from studies in mice. Very little is known about gene expression and function during human odontogenesis. Sonic Hedgehog (SHH) signaling has been de...

    Authors: Xuefeng Hu, Shuo Zhang, Guimiao Chen, Chensheng Lin, Zhen Huang, YiPing Chen and Yanding Zhang

    Citation: BMC Developmental Biology 2013 13:11

    Content type: Research article

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  33. The 14-3-3 (YWHA) proteins are central mediators in various cellular signaling pathways regulating development and growth, including cell cycle regulation. We previously reported that all seven mammalian 14-3-...

    Authors: Santanu De and Douglas Kline

    Citation: BMC Developmental Biology 2013 13:10

    Content type: Research article

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    The Erratum to this article has been published in BMC Developmental Biology 2014 14:20

  34. Tenm4 is a mouse homolog of the Drosophila gene Tenascin-m (Ten-m (Odd oz)), which functions in motor neuron routing. Recently, a genome-wide association analysis for bipolar disorder identified a new susceptibil...

    Authors: Hisashi Nakamura, Rita N Cook and Monica J Justice

    Citation: BMC Developmental Biology 2013 13:9

    Content type: Research article

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  35. The freshwater planarian Schmidtea mediterranea has emerged as a powerful model for studies of regenerative, stem cell, and germ cell biology. Whole-mount in situ hybridization (WISH) and whole-mount fluorescent

    Authors: Ryan S King and Phillip A Newmark

    Citation: BMC Developmental Biology 2013 13:8

    Content type: Methodology article

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  36. In the male germ line of Drosophila chromatin remains decondensed and highly transcribed during meiotic prophase until it is rapidly compacted. A large proportion of the cell cycle-regulated histone H3.1 is repla...

    Authors: Wolfgang Hennig and Alexandra Weyrich

    Citation: BMC Developmental Biology 2013 13:7

    Content type: Research article

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  37. The editors of BMC Developmental Biology would like to thank all our reviewers who have contributed to the journal in Volume 12 (2012).

    Authors: Philippa K Harris

    Citation: BMC Developmental Biology 2013 13:5

    Content type: Reviewer acknowledgement

    Published on:

  38. Thyroid hormones regulate growth and development. However, the molecular mechanisms by which thyroid hormone regulates cell structural development are not fully understood. The mammalian cochlea is an intrigui...

    Authors: Katherine B Szarama, Núria Gavara, Ronald S Petralia, Richard S Chadwick and Matthew W Kelley

    Citation: BMC Developmental Biology 2013 13:6

    Content type: Research article

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  39. Individual skeletal elements of the vertebrate limbs arise through a segmentation process introducing joints in specific locations. However, the molecular pathways controlling joint formation and subsequent jo...

    Authors: Akinori Kan, Toshiyuki Ikeda, Atsushi Fukai, Takumi Nakagawa, Kozo Nakamura, Ung-il Chung, Hiroshi Kawaguchi and Clifford J Tabin

    Citation: BMC Developmental Biology 2013 13:4

    Content type: Research article

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  40. Insulin and its plasma membrane receptor constitute an ancient response system critical to cell growth and differentiation. Studies using intact Rana pipiens oocytes have shown that insulin can act at receptors o...

    Authors: Gene A Morrill, Adele B Kostellow, Richard D Moore and Raj K Gupta

    Citation: BMC Developmental Biology 2013 13:3

    Content type: Research article

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  41. The members of the protein kinase C (PKC) family consist of serine/threonine kinases classified according to their regulatory domain. Those that belong to the novel PKC subfamily, such as PKCδ, are dependent o...

    Authors: Sergio Carracedo, Ursula Braun and Michael Leitges

    Citation: BMC Developmental Biology 2013 13:2

    Content type: Research article

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  42. Group B Sox domain transcription factors play important roles in metazoan central nervous system development. They are, however, difficult to study as mutations often have pleiotropic effects and other Sox fam...

    Authors: Shih Pei Shen, Jelena Aleksic and Steven Russell

    Citation: BMC Developmental Biology 2013 13:1

    Content type: Research article

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  43. Members of the family Syngnathidae share a unique reproductive mode termed male pregnancy. Males carry eggs in specialised brooding structures for several weeks and release free-swimming offspring. Here we des...

    Authors: Stefan Sommer, Camilla M Whittington and Anthony B Wilson

    Citation: BMC Developmental Biology 2012 12:39

    Content type: Research article

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