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BMC Developmental Biology

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  1. Content type: Research article

    Sex determination in mammals requires expression of the Y-linked gene Sry in the bipotential genital ridges of the XY embryo. Even minor delay of the onset of Sry expression can result in XY sex reversal, highlig...

    Authors: Christian Larney, Timothy L. Bailey and Peter Koopman

    Citation: BMC Developmental Biology 2015 15:34

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  2. Content type: Research article

    In multiple vertebrate organisms, including chick, Xenopus, and zebrafish, Fibroblast Growth Factor (FGF) and Wnt signaling cooperate during formation of the otic placode. However, in the mouse, although FGF sign...

    Authors: Kevin D. Wright, Amanda A. Mahoney Rogers, Jian Zhang and Katherine Shim

    Citation: BMC Developmental Biology 2015 15:33

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  3. Content type: Commentary

    Recent studies have identified epithelial stem and progenitor cell populations of the lung. We are just beginning to understand the mechanisms that regulate their homeostatic, regenerative and maladaptive beha...

    Authors: Matt L. Donne, Andrew J. Lechner and Jason R. Rock

    Citation: BMC Developmental Biology 2015 15:32

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  4. Content type: Research article

    It remains unclear to what extent midgut rotation determines human intestinal topography and pathology. We reinvestigated the midgut during its looping and herniation phases of development, using novel 3D visu...

    Authors: Jelly HM Soffers, Jill PJM Hikspoors, Hayelom K. Mekonen, S. Eleonore Koehler and Wouter H. Lamers

    Citation: BMC Developmental Biology 2015 15:31

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  5. Content type: Research article

    Nearly half of all individuals with Down Syndrome (DS) have some type of congenital heart defect (CHD), suggesting that DS sensitizes to CHD but does not cause it. We used a common mouse model of DS, the Ts65D...

    Authors: Renita C. Polk, Peter Gergics, Jeffrey D. Steimle, Huiqing Li, Ivan P. Moskowitz, Sally A. Camper and Roger H. Reeves

    Citation: BMC Developmental Biology 2015 15:30

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  6. Content type: Research article

    Magnetic resonance imaging (MRI) has many advantages in the research of in vivo embryonic brain development, specifically its noninvasive aspects and ability to avoid skeletal interference. However, few studie...

    Authors: Zien Zhou, Zengai Chen, Jiehui Shan, Weiwei Ma, Lei Li, Jinyan Zu and Jianrong Xu

    Citation: BMC Developmental Biology 2015 15:29

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  7. Content type: Research article

    Haploinsufficiency of the FOXL2 transcription factor in humans causes Blepharophimosis/Ptosis/Epicanthus Inversus syndrome (BPES), characterized by eyelid anomalies and premature ovarian failure. Mice lacking Fox...

    Authors: Mara Marongiu, Loredana Marcia, Emanuele Pelosi, Mario Lovicu, Manila Deiana, Yonqing Zhang, Alessandro Puddu, Angela Loi, Manuela Uda, Antonino Forabosco, David Schlessinger and Laura Crisponi

    Citation: BMC Developmental Biology 2015 15:27

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  8. Content type: Research article

    MicroRNAs (miRNAs) are small noncoding RNAs that act as post-transcriptional regulators of gene targets. Accurate quantification of miRNA expression using validated internal controls should aid in the understa...

    Authors: Mahdi Mahdipour, Helena T.A. van Tol, Tom A.E. Stout and Bernard A.J. Roelen

    Citation: BMC Developmental Biology 2015 15:25

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  9. Content type: Methodology article

    During the fourth larval (L4) stage, vulval cells of C. elegans undergo extensive morphogenesis accompanied by changes in gene expression. This phase of vulval development, occurring after the well-studied induct...

    Authors: Darren Z. L. Mok, Paul W. Sternberg and Takao Inoue

    Citation: BMC Developmental Biology 2015 15:26

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  10. Content type: Research Article

    Adult echinoderms can completely regenerate major parts of their central nervous system even after severe injuries. Even though this capacity has long been known, the molecular mechanisms that drive fast and c...

    Authors: Vladimir S Mashanov, Olga R Zueva and José E García-Arrarás

    Citation: BMC Developmental Biology 2015 15:24

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  11. Content type: Research article

    HP1γ, a well-known regulator of gene expression, has been recently identified to be a target of Aurora A, a mitotic kinase which is important for both gametogenesis and embryogenesis. The purpose of this study...

    Authors: Phoebe H. Leonard, Adrienne Grzenda, Angela Mathison, Dean E. Morbeck, Jolene R. Fredrickson, Thiago M. de Assuncao, Trace Christensen, Jeffrey Salisbury, Ezequiel Calvo, Juan Iovanna, Charles C. Coddington, Raul Urrutia and Gwen Lomberk

    Citation: BMC Developmental Biology 2015 15:23

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  12. Content type: Research article

    Despite extensive knowledge on bivalve anatomy and development, the formation and differentiation of the mantle margin and its associated organs remain largely unclear. Bivalves from the family Pectinidae (sca...

    Authors: Jorge A. Audino, José Eduardo A. R. Marian, Andreas Wanninger and Sônia G. B. C. Lopes

    Citation: BMC Developmental Biology 2015 15:22

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  13. Content type: Research article

    The mouse embryonic mandible comprises two types of tooth primordia in the cheek region: progressive tooth primordia of prospective functional teeth and rudimentary tooth primordia in premolar region – MS and ...

    Authors: Katerina Lochovska, Renata Peterkova, Zuzana Pavlikova and Maria Hovorakova

    Citation: BMC Developmental Biology 2015 15:21

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  14. Content type: Research article

    Endothelial or epithelial cellular branching is vital in development and cancer progression; however, the molecular mechanisms of these processes are not clear. In Drosophila, terminal cell at the end of some tra...

    Authors: Matthew Man-Kin Wong, Ming-Fai Liu and Sung Kay Chiu

    Citation: BMC Developmental Biology 2015 15:20

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  15. Content type: Methodology article

    The ability to visualise the expression of individual genes in situ is an invaluable tool for developmental and evolutionary biologists; it allows for the characterisation of gene function, gene regulation and th...

    Authors: Jennifer Hohagen, Ines Herlitze and Daniel John Jackson

    Citation: BMC Developmental Biology 2015 15:19

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  16. Content type: Research article

    The developing eye receives blood supply from two vascular systems, the intraocular hyaloid system and the superficial choroidal vessels. In zebrafish, a highly stereotypic and simple set of vessels develops o...

    Authors: Rivka Kaufman, Omri Weiss, Meyrav Sebbagh, Revital Ravid, Liron Gibbs-Bar, Karina Yaniv and Adi Inbal

    Citation: BMC Developmental Biology 2015 15:18

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  17. Content type: Research article

    Marsupials such as the tammar wallaby (M.Eugenii) have a short gestation (29.3 days) and at birth the altricial young resembles a fetus, and the major development occurs postnatally while the young remains in the...

    Authors: Vengamanaidu Modepalli, Lyn A Hinds, Julie A Sharp, Christophe Lefevre and Kevin R Nicholas

    Citation: BMC Developmental Biology 2015 15:16

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  18. Content type: Research article

    There is increasing evidence of a pivotal role for regulated mRNA translation in control of developmental cell fate transitions. Physiological and pathological stem and progenitor cell self-renewal is maintain...

    Authors: Angus M MacNicol, Linda L Hardy, Horace J Spencer and Melanie C MacNicol

    Citation: BMC Developmental Biology 2015 15:15

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  19. Content type: Research article

    Human dental pulp represents a suitable alternative source of stem cells for the purpose of cell-based therapies in regenerative medicine, because it is relatively easy to obtain it, using low invasive procedu...

    Authors: Alessandra Pisciotta, Gianluca Carnevale, Simona Meloni, Massimo Riccio, Sara De Biasi, Lara Gibellini, Adriano Ferrari, Giacomo Bruzzesi and Anto De Pol

    Citation: BMC Developmental Biology 2015 15:14

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  20. Content type: Research article

    In mammals, maternal differentially methylated regions (DMRs) acquire DNA methylation during the postnatal growth stage of oogenesis, with paternal DMRs acquiring DNA methylation in the perinatal prospermatago...

    Authors: Alan M O’Doherty, David A Magee, Lynee C O’Shea, Niamh Forde, Marijke E Beltman, Solomon Mamo and Trudee Fair

    Citation: BMC Developmental Biology 2015 15:13

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  21. Content type: Research article

    Central American crater lake cichlid fish of the Midas species complex (Amphilophus spp.) are a model system for sympatric speciation and fast ecological diversification and specialization. Midas cichlids have be...

    Authors: Claudius F Kratochwil, Maggie M Sefton and Axel Meyer

    Citation: BMC Developmental Biology 2015 15:12

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  22. Content type: Methodology article

    Tissue fixation is crucial for preserving the morphology of biological structures and cytological details to prevent postmortem degradation and autolysis. Improper fixation conditions could lead to artifacts a...

    Authors: Jing Nie, Simpla Mahato and Andrew C Zelhof

    Citation: BMC Developmental Biology 2015 15:10

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2016 Journal Metrics

  • Citation Impact
    2.280 - 2-year Impact Factor
    2.616 - 5-year Impact Factor
    0.708 - Source Normalized Impact per Paper (SNIP)
    1.353 - SCImago Journal Rank (SJR)

    1092.5 Usage Factor

    Social Media Impact
    43 Mentions