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BMC Developmental Biology

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  1. Content type: Methodology article

    Magnetic resonance imaging is a noninvasive method of evaluating embryonic development. Diffusion tensor imaging (DTI), based on the directional diffusivity of water molecules, is an established method of eval...

    Authors: Zien Zhou, Zachary DelProposto, Lianming Wu, Jianrong Xu, Jia Hua, Yan Zhou, Yongquan Ye, Zishu Zhang, Jiani Hu and E Mark Haacke

    Citation: BMC Developmental Biology 2012 12:38

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  2. Content type: Research article

    Genetic studies in mouse have demonstrated the crucial function of PAX4 in pancreatic cell differentiation. This transcription factor specifies β- and δ-cell fate at the expense of α-cell identity by repressing A...

    Authors: Joachim Djiotsa, Vincianne Verbruggen, Jean Giacomotto, Minaka Ishibashi, Elisabeth Manning, Silke Rinkwitz, Isabelle Manfroid, Marianne L Voz and Bernard Peers

    Citation: BMC Developmental Biology 2012 12:37

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  3. Content type: Research article

    In mammals, R-spondin (Rspo), an activator of the Wnt/β-catenin signaling pathway, has been shown to be involved in ovarian differentiation. However, the role of the Rspo/Wnt/β-catenin signaling pathway in fis...

    Authors: Linyan Zhou, Tapas Charkraborty, Xiangguo Yu, Limin Wu, Gang Liu, Sipra Mohapatra, Deshou Wang and Yoshitaka Nagahama

    Citation: BMC Developmental Biology 2012 12:36

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  4. Content type: Research article

    The proper balance of autophagy, a lysosome-mediated degradation process, is indispensable for oogenesis in Drosophila. We recently demonstrated that egg development depends on autophagy in the somatic follicle c...

    Authors: Julia MI Barth, Ernst Hafen and Katja Köhler

    Citation: BMC Developmental Biology 2012 12:35

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  5. Content type: Research article

    The contribution of cell proliferation to regeneration varies greatly between different metazoan models. Planarians rely on pluripotent neoblasts and amphibian limb regeneration depends upon formation of a pro...

    Authors: Yale J Passamaneck and Mark Q Martindale

    Citation: BMC Developmental Biology 2012 12:34

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  6. Content type: Research article

    The first distinct differentiation event in mammals occurs at the blastocyst stage when totipotent blastomeres differentiate into either pluripotent inner cell mass (ICM) or multipotent trophectoderm (TE). Her...

    Authors: Manabu Ozawa, Miki Sakatani, JiQiang Yao, Savita Shanker, Fahong Yu, Rui Yamashita, Shunichi Wakabayashi, Kenta Nakai, Kyle B Dobbs, Mateus José Sudano, William G Farmerie and Peter J Hansen

    Citation: BMC Developmental Biology 2012 12:33

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  7. Content type: Research article

    Temperature affects virtually all cellular processes. A quick increase in temperature challenges the cells to undergo a heat shock response to maintain cellular homeostasis. Heat shock factor-1 (HSF-1) functio...

    Authors: János Barna, Andrea Princz, Mónika Kosztelnik, Balázs Hargitai, Krisztina Takács-Vellai and Tibor Vellai

    Citation: BMC Developmental Biology 2012 12:32

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  8. Content type: Research article

    Oxygen sensing is a near universal signaling modality that, in eukaryotes ranging from protists such as Dictyostelium and Toxoplasma to humans, involves a cytoplasmic prolyl 4-hydroxylase that utilizes oxygen and...

    Authors: Yuechi Xu, Zhuo A Wang, Rebekah S Green and Christopher M West

    Citation: BMC Developmental Biology 2012 12:31

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  9. Content type: Research article

    Embryonic development proceeds through finely tuned reprogramming of the parental genomes to form a totipotent embryo. Cells within this embryo will then differentiate and give rise to all the tissues of a new...

    Authors: Tiphaine Aguirre-Lavin, Pierre Adenot, Amélie Bonnet-Garnier, Gaétan Lehmann, Renaud Fleurot, Claire Boulesteix, Pascale Debey and Nathalie Beaujean

    Citation: BMC Developmental Biology 2012 12:30

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  10. Content type: Research article

    Hox proteins are transcription factors involved in crucial processes during animal development. Their mode of action remains scantily documented. While other families of transcription factors, like Smad or Sta...

    Authors: Barbara Lambert, Julie Vandeputte, Sophie Remacle, Isabelle Bergiers, Nicolas Simonis, Jean-Claude Twizere, Marc Vidal and René Rezsohazy

    Citation: BMC Developmental Biology 2012 12:29

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  11. Content type: Research article

    In chondrichthyans, basal osteichthyans and tetrapods, vertebral bodies have cartilaginous anlagen that subsequently mineralize (chondrichthyans) or ossify (osteichthyans). Chondrocytes that form the vertebral...

    Authors: Anabela Bensimon-Brito, João Cardeira, Maria Leonor Cancela, Ann Huysseune and Paul Eckhard Witten

    Citation: BMC Developmental Biology 2012 12:28

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  12. Content type: Research article

    Secreted frizzled-related proteins (SFRPs) are a family of proteins that block the Wnt signaling pathway and loss of SFRP1 expression is found in breast cancer along with a multitude of other human cancers. Ac...

    Authors: Kelly J Gauger, Akihiko Shimono, Giovanna M Crisi and Sallie Smith Schneider

    Citation: BMC Developmental Biology 2012 12:25

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  13. Content type: Research article

    The multicellular slug in Dictyostelium has a single tip that acts as an organising centre patterning the rest of the slug. High adenosine levels at the tip are believed to be responsible for this tip dominance a...

    Authors: Pundrik Jaiswal, Shashi Prakash Singh, Prasad Aiyar, Rakhil Akkali and Ramamurthy Baskar

    Citation: BMC Developmental Biology 2012 12:26

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  14. Content type: Research article

    Zebrafish has emerged as a powerful model organism to study the process of regeneration. This teleost fish has the ability to regenerate various tissues and organs like the heart, spinal cord, retina and fins....

    Authors: Ana Sofia Azevedo, Sara Sousa, António Jacinto and Leonor Saúde

    Citation: BMC Developmental Biology 2012 12:24

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  15. Content type: Research article

    Mouse limb bud is a prime model to study the regulatory interactions that control vertebrate organogenesis. Major aspects of limb bud development are controlled by feedback loops that define a self-regulatory ...

    Authors: Aimée Zuniga, Frédéric Laurent, Javier Lopez-Rios, Christian Klasen, Nicolas Matt and Rolf Zeller

    Citation: BMC Developmental Biology 2012 12:23

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  16. Content type: Research article

    Valvulogenesis and septation in the developing heart depend on the formation and remodeling of endocardial cushions in the atrioventricular canal (AVC) and outflow tract (OFT). These cushions are invaded by a ...

    Authors: Kathryn E LeMasters, Yotam Blech-Hermoni, Samantha J Stillwagon, Natalie A Vajda and Andrea N Ladd

    Citation: BMC Developmental Biology 2012 12:22

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  17. Content type: Research article

    Calpains are calcium regulated intracellular cysteine proteases implicated in a variety of physiological functions and pathological conditions. The Drosophila melanogaster genome contains only two genes, CalpA an...

    Authors: Endre Kókai, Ferencz Sándor Páldy, Kálmán Somogyi, Anil Chougule, Margit Pál, Éva Kerekes, Péter Deák, Péter Friedrich, Viktor Dombrádi and Géza Ádám

    Citation: BMC Developmental Biology 2012 12:20

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  18. Content type: Research article

    The peptidylarginine deiminases (PADIs) convert positively charged arginine residues to neutrally charged citrulline on protein substrates in a process that is known as citrullination or deimination. Previous ...

    Authors: Rui Kan, Mei Jin, Venkataraman Subramanian, Corey P Causey, Paul R Thompson and Scott A Coonrod

    Citation: BMC Developmental Biology 2012 12:19

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  19. Content type: Methodology article

    To facilitate the in vivo study of esophageal (stem) cell biology in homeostasis and cancer, novel mouse models are necessary to elicit expression of candidate genes in a tissue-specific and inducible fashion. To...

    Authors: Sabrina Roth, Patrick Franken, Kim Monkhorst, John Kong a San and Riccardo Fodde

    Citation: BMC Developmental Biology 2012 12:18

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  20. Content type: Research article

    Wnts are a family of secreted signaling molecules involved in a number of developmental processes including the establishment of cell fate, polarity and proliferation. Recent studies also implicate wnts in epi...

    Authors: Macalister Usongo and Riaz Farookhi

    Citation: BMC Developmental Biology 2012 12:17

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  21. Content type: Research article

    Histone deacetylase-4 (Hdac4) is a class II histone deacetylase that inhibits the activity of transcription factors. In humans, HDAC4 deficiency is associated with non-syndromic oral clefts and brachydactyly m...

    Authors: April DeLaurier, Yukio Nakamura, Ingo Braasch, Vishesh Khanna, Hiroyuki Kato, Shigeyuki Wakitani, John H Postlethwait and Charles B Kimmel

    Citation: BMC Developmental Biology 2012 12:16

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  22. Content type: Research article

    A hallmark of Drosophila segmentation is the stepwise subdivision of the body into smaller and smaller units, and finally into the segments. This is achieved by the function of the well-understood segmentation ge...

    Authors: Ralf Janssen, Wim G M Damen and Graham E Budd

    Citation: BMC Developmental Biology 2012 12:15

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  23. Content type: Research article

    A metamorphic life-history is present in the majority of animal phyla. This developmental mode is particularly prominent among marine invertebrates with a bentho-planktonic life cycle, where a pelagic larval f...

    Authors: Josh Sutherby, Jamie-Lee Giardini, Julia Nguyen, Gary Wessel, Mariana Leguia and Andreas Heyland

    Citation: BMC Developmental Biology 2012 12:14

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    The Erratum to this article has been published in BMC Developmental Biology 2013 13:30

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2016 Journal Metrics

  • Citation Impact
    2.280 - 2-year Impact Factor
    2.616 - 5-year Impact Factor
    0.708 - Source Normalized Impact per Paper (SNIP)
    1.353 - SCImago Journal Rank (SJR)

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