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Page 9 of 19

  1. Content type: Research article

    Teneurins are transmembrane proteins that assist morphogenetic processes in many organisms. ten-1 is the C. elegans teneurin homolog with two transcripts, ten-1a and ten-1b, that respectively encode a long (TEN-1...

    Authors: Catarina Mörck, Vivekanand Vivekanand, Gholamali Jafari and Marc Pilon

    Citation: BMC Developmental Biology 2010 10:55

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  2. Content type: Research article

    Vertebrates show clear asymmetry in left-right (L-R) patterning of their organs and associated vasculature. During mammalian development a cilia driven leftwards flow of liquid leads to the left-sided expressi...

    Authors: Jonathan Stevens, Alexander Ermakov, Jose Braganca, Helen Hilton, Peter Underhill, Shoumo Bhattacharya, Nigel A Brown and Dominic P Norris

    Citation: BMC Developmental Biology 2010 10:54

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  3. Content type: Methodology article

    The red flour beetle Tribolium castaneum has developed into an insect model system second only to Drosophila. Moreover, as a coleopteran it represents the most species-rich metazoan taxon which also includes many...

    Authors: Johannes B Schinko, Markus Weber, Ivana Viktorinova, Alexandros Kiupakis, Michalis Averof, Martin Klingler, Ernst A Wimmer and Gregor Bucher

    Citation: BMC Developmental Biology 2010 10:53

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  4. Content type: Research article

    The neural crest is a group of multipotent cells that emerges after an epithelial-to-mesenchymal transition from the dorsal neural tube early during development. These cells then migrate throughout the embryo,...

    Authors: Michelle Reyes, Katrina Zandberg, Iska Desmawati and Maria E de Bellard

    Citation: BMC Developmental Biology 2010 10:52

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  5. Content type: Research article

    Growth factors and their receptors are mediators of organogenesis and must be tightly regulated in a temporal and spatial manner for proper tissue morphogenesis. Intracellular regulators of growth factor signa...

    Authors: Xuehui Yang, Sean Kilgallen, Viktoria Andreeva, Douglas B Spicer, Ilka Pinz and Robert Friesel

    Citation: BMC Developmental Biology 2010 10:48

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  6. Content type: Research article

    Several imprinted genes have been implicated in the process of placentation. The distal region of mouse chromosome 7 (Chr 7) contains at least ten imprinted genes, several of which are expressed from the mater...

    Authors: Rosemary Oh-McGinnis, Aaron B Bogutz, Kang Yun Lee, Michael J Higgins and Louis Lefebvre

    Citation: BMC Developmental Biology 2010 10:50

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  7. Content type: Research article

    Adipocyte hyperplasia is associated with obesity and arises due to adipogenic differentiation of resident multipotent stem cells in the vascular stroma of adipose tissue and remote stem cells of other organs. ...

    Authors: Shu-Wen Qian, Xi Li, You-You Zhang, Hai-Yan Huang, Yuan Liu, Xia Sun and Qi-Qun Tang

    Citation: BMC Developmental Biology 2010 10:47

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  8. Content type: Research article

    The C. elegans gene folt-1 is an ortholog of the human reduced folate carrier gene. The FOLT-1 protein has been shown to transport folate and to be involved in uptake of exogenous folate by worms. A knockout muta...

    Authors: Misa U Austin, Wei-Siang Liau, Krishnaswamy Balamurugan, Balasubramaniem Ashokkumar, Hamid M Said and Craig W LaMunyon

    Citation: BMC Developmental Biology 2010 10:46

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  9. Content type: Research article

    Numerous cases of predator-induced polyphenisms, in which alternate phenotypes are produced in response to extrinsic stimuli, have been reported in aquatic taxa to date. The genus Daphnia (Branchiopoda, Cladocera...

    Authors: Hitoshi Miyakawa, Maki Imai, Naoki Sugimoto, Yuki Ishikawa, Asano Ishikawa, Hidehiko Ishigaki, Yasukazu Okada, Satoshi Miyazaki, Shigeyuki Koshikawa, Richard Cornette and Toru Miura

    Citation: BMC Developmental Biology 2010 10:45

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  10. Content type: Research article

    The zinc-finger transcription factor GLI3 is an important mediator of Sonic hedgehog signaling and crucial for patterning of many aspects of the vertebrate body plan. In vertebrates, the mechanism of SHH signa...

    Authors: Amir A Abbasi, Zissis Paparidis, Sajid Malik, Fiona Bangs, Ansgar Schmidt, Sabine Koch, Javier Lopez-Rios and Karl-Heinz Grzeschik

    Citation: BMC Developmental Biology 2010 10:44

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  11. Content type: Research article

    Red algae are primitive photosynthetic eukaryotes, whose spores are ideal subjects for studies of photosynthesis and development. Although the development of red alga spores has received considerable research ...

    Authors: Xiujun Xie, Guangce Wang, Guanghua Pan, Shan Gao, Pu Xu and Jianyi Zhu

    Citation: BMC Developmental Biology 2010 10:43

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  12. Content type: Research article

    Many species form extraembryonic tissues during embryogenesis, such as the placenta of humans and other viviparous mammals. Extraembryonic tissues have various roles in protecting, nourishing and patterning em...

    Authors: Sung-Kook Hong, Carly S Levin, Jamie L Brown, Haiyan Wan, Brad T Sherman, Da Wei Huang, Richard A Lempicki and Benjamin Feldman

    Citation: BMC Developmental Biology 2010 10:42

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  13. Content type: Research article

    The transcription factor Pax6 functions in the specification and maintenance of the differentiated cell lineages in the endocrine pancreas. It has two DNA binding domains, the paired domain and the homeodomain...

    Authors: Petra Dames, Ramona Puff, Michaela Weise, Klaus G Parhofer, Burkhard Göke, Magdalena Götz, Jochen Graw, Jack Favor and Andreas Lechner

    Citation: BMC Developmental Biology 2010 10:39

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  14. Content type: Research article

    The C-terminal Eps15 homology domain-containing protein 1 (EHD1) is ubiquitously expressed and regulates the endocytic trafficking and recycling of membrane components and several transmembrane receptors. To e...

    Authors: Mark A Rainey, Manju George, GuoGuang Ying, Reiko Akakura, Daniel J Burgess, Ed Siefker, Tom Bargar, Lynn Doglio, Susan E Crawford, Gordon L Todd, Venkatesh Govindarajan, Rex A Hess, Vimla Band, Mayumi Naramura and Hamid Band

    Citation: BMC Developmental Biology 2010 10:37

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  15. Content type: Research article

    Six3a belongs to the SIX family of homeodomain proteins and is expressed in the most anterior neural plate at the beginning of neurogenesis in various species. Though the function of Six3a as a crucial regulat...

    Authors: Chung-Hao Chao, Horng-Dar Wang and Chiou-Hwa Yuh

    Citation: BMC Developmental Biology 2010 10:35

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  16. Content type: Research article

    Pattern formation of the limb skeleton is regulated by a complex interplay of signaling centers located in the ectodermal sheath and mesenchymal core of the limb anlagen, which results, in the forelimb, in the...

    Authors: Poongodi Geetha-Loganathan, Suresh Nimmagadda, Bodo Christ, Ruijin Huang and Martin Scaal

    Citation: BMC Developmental Biology 2010 10:32

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  17. Content type: Research article

    The interaction between the karyoplast and cytoplast plays an important role in the efficiency of somatic cell nuclear transfer (SCNT), but the underlying mechanism remains unclear. It is generally accepted th...

    Authors: Zhong-hai Yan, Yi-ye Zhou, Jing Fu, Fei Jiao, Lei-wen Zhao, Peng-fei Guan, Shu-zhen Huang, Yi-tao Zeng and Fanyi Zeng

    Citation: BMC Developmental Biology 2010 10:31

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  18. Content type: Research article

    Endogenous peptides such as neuropeptides are involved in numerous biological processes in the fully developed brain but very little is known about their role in brain development. Japanese quail is a commonly...

    Authors: Birger Scholz, Henrik Alm, Anna Mattsson, Anna Nilsson, Kim Kultima, Mikhail M Savitski, Maria Fälth, Karl Sköld, Björn Brunström, Per E Andren and Lennart Dencker

    Citation: BMC Developmental Biology 2010 10:30

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  19. Content type: Research article

    Very little is known about how intervertebral disc (IVD) is formed or maintained. Members of the TGF-β superfamily are secreted signaling proteins that regulate many aspects of development including cellular d...

    Authors: Philip Sohn, Megan Cox, Dongquan Chen and Rosa Serra

    Citation: BMC Developmental Biology 2010 10:29

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  20. Content type: Research article

    Cloning of cattle by somatic cell nuclear transfer (SCNT) is associated with a high incidence of pregnancy failure characterized by abnormal placental and foetal development. These abnormalities are thought to...

    Authors: Christine Couldrey and Rita SF Lee

    Citation: BMC Developmental Biology 2010 10:27

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  21. Content type: Research article

    Somitogenesis is the earliest sign of segmentation in the developing vertebrate embryo. This process starts very early, soon after gastrulation has initiated and proceeds in an anterior-to-posterior direction ...

    Authors: Gennady Tenin, David Wright, Zoltan Ferjentsik, Robert Bone, Michael J McGrew and Miguel Maroto

    Citation: BMC Developmental Biology 2010 10:24

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  22. Content type: Research article

    The mosquito A. aegypti is vector of dengue and other viruses. New methods of vector control are needed and can be achieved by a better understanding of the life cycle of this insect. Embryogenesis is a part of A...

    Authors: Wagner Vital, Gustavo Lazzaro Rezende, Leonardo Abreu, Jorge Moraes, Francisco JA Lemos, Itabajara da Silva Vaz Jr and Carlos Logullo

    Citation: BMC Developmental Biology 2010 10:25

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  23. Content type: Research article

    Regulatory elements that control expression of specific genes during development have been shown in many cases to contain functionally-conserved modules that can be transferred between species and direct gene ...

    Authors: Michael J McGrew, Adrian Sherman, Simon G Lillico, Lorna Taylor and Helen Sang

    Citation: BMC Developmental Biology 2010 10:26

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  24. Content type: Research article

    Decapentaplegic (Dpp) is one of the best characterized morphogens, required for dorso-ventral patterning of the Drosophila embryo and for anterior-posterior (A/P) patterning of the wing imaginal disc. In the larv...

    Authors: Jie Shen, Christian Dahmann and Gert O Pflugfelder

    Citation: BMC Developmental Biology 2010 10:23

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  25. Content type: Research article

    Apert syndrome is characterized by craniosynostosis and limb abnormalities and is primarily caused by FGFR2 +/P253R and +/S252W mutations. The former mutation is present in approximately one third whereas the ...

    Authors: Yingli Wang, Miao Sun, Victoria L Uhlhorn, Xueyan Zhou, Inga Peter, Neus Martinez-Abadias, Cheryl A Hill, Christopher J Percival, Joan T Richtsmeier, David L Huso and Ethylin Wang Jabs

    Citation: BMC Developmental Biology 2010 10:22

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  26. Content type: Research article

    Postnatal growth in mouse is rapid, with total skeletal muscle mass increasing several-fold in the first few weeks. Muscle growth can be achieved by either an increase in muscle fibre number or an increase in ...

    Authors: Robert B White, Anne-Sophie Biérinx, Viola F Gnocchi and Peter S Zammit

    Citation: BMC Developmental Biology 2010 10:21

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  27. Content type: Research article

    In a large number of studies, members of the microRNA (miRNA)-34 family such as miRNA-34a, miRNA-34b, miRNA-34c, as well as miRNA-125b and miRNA-155, have been shown to be regulators of apoptosis. The ability ...

    Authors: Keren Gueta, Natali Molotski, Natalie Gerchikov, Eyal Mor, Shoshana Savion, Amos Fein, Vladimir Toder, Noam Shomron and Arkady Torchinsky

    Citation: BMC Developmental Biology 2010 10:20

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  28. Content type: Research article

    The vertebrate pancreas contains islet, acinar and ductal cells. These cells derive from a transient pool of multipotent pancreatic progenitors during embryonic development. Insight into the genetic determinan...

    Authors: Shuai Li, Adam B Francisco, Robert J Munroe, John C Schimenti and Qiaoming Long

    Citation: BMC Developmental Biology 2010 10:19

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  29. Content type: Methodology article

    Growing demand for three dimensional (3D) digital images of embryos for purposes of phenotypic assessment drives implementation of new histological and imaging techniques. Among these micro-computed tomography...

    Authors: Eric J Schmidt, Trish E Parsons, Heather A Jamniczky, Julian Gitelman, Cvett Trpkov, Julia C Boughner, C Cairine Logan, Christoph W Sensen and Benedikt Hallgrímsson

    Citation: BMC Developmental Biology 2010 10:18

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  30. Content type: Research article

    The chick middle ear bone, the columella, provides an accessible model in which to study the tissue and molecular interactions necessary for induction and patterning of the columella, as well as associated mul...

    Authors: Jamie L Wood, Ami J Hughes, Kathryn J Mercer and Susan C Chapman

    Citation: BMC Developmental Biology 2010 10:16

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  31. Content type: Research article

    The tetracycline-inducible gene regulation system is a powerful tool that allows temporal and dose-dependent regulation of target transgene expression in vitro and in vivo. Several tetracycline-inducible trans...

    Authors: Yi Sheng, Chih-Cheng Lin, Junming Yue, Meena Sukhwani, Jennifer J Shuttleworth, Tianjiao Chu and Kyle E Orwig

    Citation: BMC Developmental Biology 2010 10:17

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  32. Content type: Research article

    Axolotls have the unique ability, among vertebrates, to perfectly regenerate complex body parts, such as limbs, after amputation. In addition, axolotls pattern developing and regenerating autopods from the ant...

    Authors: Jean-Charles Guimond, Mathieu Lévesque, Pierre-Luc Michaud, Jérémie Berdugo, Kenneth Finnson, Anie Philip and Stéphane Roy

    Citation: BMC Developmental Biology 2010 10:15

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  33. Content type: Research article

    Astacins are a large family of zinc metalloproteases found in bacteria and animals. They have diverse roles ranging from digestion of food to processing of extracellular matrix components. The C. elegans genome c...

    Authors: Ja-On Park, Jie Pan, Frank Möhrlen, Marcus-Oliver Schupp, Robert Johnsen, David L Baillie, Richard Zapf, Donald G Moerman and Harald Hutter

    Citation: BMC Developmental Biology 2010 10:14

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  34. Content type: Research article

    Mammalian Ras genes regulate diverse cellular processes including proliferation and differentiation and are frequently mutated in human cancers. Tumor development in response to Ras activation varies between d...

    Authors: Daniel Burgess, Yan Zhang, Ed Siefker, Ryan Vaca, Murali R Kuracha, Lixing Reneker, Paul A Overbeek and Venkatesh Govindarajan

    Citation: BMC Developmental Biology 2010 10:13

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  35. Content type: Research article

    In embryos the maternal-to-zygotic transition (MTZ) integrates post-transcriptional regulation of maternal transcripts with transcriptional activation of the zygotic genome. Although the molecular mechanisms u...

    Authors: Paolo Gabrieli, Andrea Falaguerra, Paolo Siciliano, Ludvik M Gomulski, Francesca Scolari, Antigone Zacharopoulou, Gerald Franz, Anna R Malacrida and Giuliano Gasperi

    Citation: BMC Developmental Biology 2010 10:12

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  36. Content type: Research article

    The Class II DNA transposons are mobile genetic elements that move DNA sequence from one position in the genome to another. We have previously demonstrated that the naturally occurring Tol2 element from Oryzias l...

    Authors: Donald A Yergeau, Clair M Kelley, Emin Kuliyev, Haiqing Zhu, Amy K Sater, Dan E Wells and Paul E Mead

    Citation: BMC Developmental Biology 2010 10:11

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  37. Content type: Research article

    Bats comprise the second largest order of mammals. However, there are far fewer morphological studies of post-implantation embryonic development than early embryonic development in bats.

    Authors: Zhe Wang, Naijian Han, Paul A Racey, Binghua Ru and Guimei He

    Citation: BMC Developmental Biology 2010 10:10

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  38. Content type: Research article

    The Ly-6 (Ly-6/uPAR) superfamily members share the Ly-6 domain defined by distinct disulfide bonding patterns between 8 or 10 cysteine residues. They comprise membrane- and secretory-type proteins. We recently...

    Authors: Koichi Ushizawa, Toru Takahashi, Misa Hosoe, Keiichiro Kizaki and Kazuyoshi Hashizume

    Citation: BMC Developmental Biology 2010 10:9

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  39. Content type: Research article

    Retinal cell development has been extensively investigated; however, the current knowledge of dynamic morphological and molecular changes is not yet complete.

    Authors: Sung Tae Doh, Hailing Hao, Stephanie C Loh, Tapan Patel, Haim Y Tawil, David K Chen, Anna Pashkova, Andy Shen, Huimin Wang and Li Cai

    Citation: BMC Developmental Biology 2010 10:8

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  40. Content type: Research article

    The transcription factor Pax6 is essential for the development of the central nervous system and it exerts its multiple functions by regulating the expression of downstream target molecules. To screen for gene...

    Authors: Keiko Numayama-Tsuruta, Yoko Arai, Masanori Takahashi, Makiko Sasaki-Hoshino, Nobuo Funatsu, Shun Nakamura and Noriko Osumi

    Citation: BMC Developmental Biology 2010 10:6

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  41. Content type: Research article

    The J-domain-containing protein auxilin, a critical regulator in clathrin-mediated transport, has been implicated in Drosophila Notch signaling. To ask if this role of auxilin is conserved and whether auxilin has...

    Authors: Ting Bai, Jamie L Seebald, Kyu-Eui Kim, Hong-Mei Ding, Daniel P Szeto and Henry C Chang

    Citation: BMC Developmental Biology 2010 10:7

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