Citation Impact
2.000 - 2-year Impact Factor
2.643 - 5-year Impact Factor
0.788 - Source Normalized Impact per Paper (SNIP)
1.109 - SCImago Journal Rank (SJR)
Usage
273,615 Downloads
203 Altmetric Mentions
Page 4 of 20
Pluripotent cells are present in early embryos until the levels of the pluripotency regulator Oct4 drop at the beginning of somitogenesis. Elevating Oct4 levels in explanted post-pluripotent cells in vitro res...
Citation: BMC Developmental Biology 2015 15:35
Sex determination in mammals requires expression of the Y-linked gene Sry in the bipotential genital ridges of the XY embryo. Even minor delay of the onset of Sry expression can result in XY sex reversal, highlig...
Citation: BMC Developmental Biology 2015 15:34
In multiple vertebrate organisms, including chick, Xenopus, and zebrafish, Fibroblast Growth Factor (FGF) and Wnt signaling cooperate during formation of the otic placode. However, in the mouse, although FGF sign...
Citation: BMC Developmental Biology 2015 15:33
Recent studies have identified epithelial stem and progenitor cell populations of the lung. We are just beginning to understand the mechanisms that regulate their homeostatic, regenerative and maladaptive beha...
Citation: BMC Developmental Biology 2015 15:32
It remains unclear to what extent midgut rotation determines human intestinal topography and pathology. We reinvestigated the midgut during its looping and herniation phases of development, using novel 3D visu...
Citation: BMC Developmental Biology 2015 15:31
Nearly half of all individuals with Down Syndrome (DS) have some type of congenital heart defect (CHD), suggesting that DS sensitizes to CHD but does not cause it. We used a common mouse model of DS, the Ts65D...
Citation: BMC Developmental Biology 2015 15:30
Magnetic resonance imaging (MRI) has many advantages in the research of in vivo embryonic brain development, specifically its noninvasive aspects and ability to avoid skeletal interference. However, few studie...
Citation: BMC Developmental Biology 2015 15:29
The 39 mammalian Hox genes show problematic patterns of functional overlap. In order to more fully define the developmental roles of Hox genes it is necessary to remove multiple combinations of paralogous and ...
Citation: BMC Developmental Biology 2015 15:28
Haploinsufficiency of the FOXL2 transcription factor in humans causes Blepharophimosis/Ptosis/Epicanthus Inversus syndrome (BPES), characterized by eyelid anomalies and premature ovarian failure. Mice lacking Fox...
Citation: BMC Developmental Biology 2015 15:27
During the fourth larval (L4) stage, vulval cells of C. elegans undergo extensive morphogenesis accompanied by changes in gene expression. This phase of vulval development, occurring after the well-studied induct...
Citation: BMC Developmental Biology 2015 15:26
MicroRNAs (miRNAs) are small noncoding RNAs that act as post-transcriptional regulators of gene targets. Accurate quantification of miRNA expression using validated internal controls should aid in the understa...
Citation: BMC Developmental Biology 2015 15:25
Adult echinoderms can completely regenerate major parts of their central nervous system even after severe injuries. Even though this capacity has long been known, the molecular mechanisms that drive fast and c...
Citation: BMC Developmental Biology 2015 15:24
HP1γ, a well-known regulator of gene expression, has been recently identified to be a target of Aurora A, a mitotic kinase which is important for both gametogenesis and embryogenesis. The purpose of this study...
Citation: BMC Developmental Biology 2015 15:23
Despite extensive knowledge on bivalve anatomy and development, the formation and differentiation of the mantle margin and its associated organs remain largely unclear. Bivalves from the family Pectinidae (sca...
Citation: BMC Developmental Biology 2015 15:22
The mouse embryonic mandible comprises two types of tooth primordia in the cheek region: progressive tooth primordia of prospective functional teeth and rudimentary tooth primordia in premolar region – MS and ...
Citation: BMC Developmental Biology 2015 15:21
Endothelial or epithelial cellular branching is vital in development and cancer progression; however, the molecular mechanisms of these processes are not clear. In Drosophila, terminal cell at the end of some tra...
Citation: BMC Developmental Biology 2015 15:20
The ability to visualise the expression of individual genes in situ is an invaluable tool for developmental and evolutionary biologists; it allows for the characterisation of gene function, gene regulation and th...
Citation: BMC Developmental Biology 2015 15:19
The developing eye receives blood supply from two vascular systems, the intraocular hyaloid system and the superficial choroidal vessels. In zebrafish, a highly stereotypic and simple set of vessels develops o...
Citation: BMC Developmental Biology 2015 15:18
Butterfly wing color patterns emerge as the result of a regular arrangement of scales produced by epithelial scale cells at the pupal stage. These color patterns and scale arrangements are coordinated througho...
Citation: BMC Developmental Biology 2015 15:17
Marsupials such as the tammar wallaby (M.Eugenii) have a short gestation (29.3 days) and at birth the altricial young resembles a fetus, and the major development occurs postnatally while the young remains in the...
Citation: BMC Developmental Biology 2015 15:16
There is increasing evidence of a pivotal role for regulated mRNA translation in control of developmental cell fate transitions. Physiological and pathological stem and progenitor cell self-renewal is maintain...
Citation: BMC Developmental Biology 2015 15:15
Human dental pulp represents a suitable alternative source of stem cells for the purpose of cell-based therapies in regenerative medicine, because it is relatively easy to obtain it, using low invasive procedu...
Citation: BMC Developmental Biology 2015 15:14
In mammals, maternal differentially methylated regions (DMRs) acquire DNA methylation during the postnatal growth stage of oogenesis, with paternal DMRs acquiring DNA methylation in the perinatal prospermatago...
Citation: BMC Developmental Biology 2015 15:13
Central American crater lake cichlid fish of the Midas species complex (Amphilophus spp.) are a model system for sympatric speciation and fast ecological diversification and specialization. Midas cichlids have be...
Citation: BMC Developmental Biology 2015 15:12
Drosophila larvae have been used as a model to study to genetic and cellular circuitries modulating behaviors. One of the challenges in behavioral study is the quantification of complex phenoty...
Citation: BMC Developmental Biology 2015 15:11
Tissue fixation is crucial for preserving the morphology of biological structures and cytological details to prevent postmortem degradation and autolysis. Improper fixation conditions could lead to artifacts a...
Citation: BMC Developmental Biology 2015 15:10
Primary cilia are essential for Hedgehog (Hh) signal transduction in vertebrates. Although the core components of the Hh pathway are highly conserved, the dependency on cilia in Hh signaling is considered to b...
Citation: BMC Developmental Biology 2015 15:9
Stem cells can respond to environmental and physiological inputs to adaptively remodel tissues. Little is known about whether stem cell niches are similarly responsive. The Drosophila ovary germline stem cell (GS...
Citation: BMC Developmental Biology 2015 15:8
Alveoli, the milk-producing units of the mammary gland, are generated during pregnancy by collaboration of different epithelial cell types. We present the first analysis of transcriptional changes within the h...
Citation: BMC Developmental Biology 2015 15:7
We have revealed that the type II diacylglycerol kinases (DGKs) δ, η and κ were expressed in the testis and ovary. However, these enzymes’ functions in the reproductive organs remain unknown.
Citation: BMC Developmental Biology 2015 15:6
The editors of BMC Developmental Biology would like to thank all our reviewers who have contributed to the journal in Volume 14 (2014).
Citation: BMC Developmental Biology 2015 15:5
In society, there is a clear need to improve the success rate of techniques to restore fertility. Therefore a deeper knowledge of the dynamics of the complex molecular environment that regulates human gametoge...
Citation: BMC Developmental Biology 2015 15:4
Dietary interventions during pregnancy alter offspring fitness. We have shown mouse maternal low protein diet fed exclusively for the preimplantation period (Emb-LPD) before return to normal protein diet (NPD)...
Citation: BMC Developmental Biology 2015 15:3
Planarians are an attractive model organism for studying stem cell-based regeneration due to their ability to replace all of their tissues from a population of adult stem cells. The molecular toolkit for plana...
Citation: BMC Developmental Biology 2015 15:2
Bioelectric phenomena have been found to exert influence on various developmental and regenerative processes. Little is known about their possible functions and the cellular mechanisms by which they might act ...
Citation: BMC Developmental Biology 2015 15:1
Zebrafish are able to regenerate many of its tissues and organs after damage. In amphibians this process is regulated by nerve fibres present at the site of injury, which have been proposed to release factors ...
Citation: BMC Developmental Biology 2014 14:49
Mapping of tissue structure at the cellular, circuit, and organ-wide scale is important for understanding physiological and biological functions. A bio-electrochemical technique known as CLARITY used for three...
Citation: BMC Developmental Biology 2014 14:48
Efforts to elucidate the cellular and molecular mechanisms of regeneration have required the application of methods to detect specific cell types and tissues in a growing cohort of experimental animal models. ...
Citation: BMC Developmental Biology 2014 14:45
Identification and characterization of molecular controls that regulate mammary stem and progenitor cell homeostasis are critical to our understanding of normal mammary gland development and its pathology.
Citation: BMC Developmental Biology 2014 14:47
In standard cell division, the cells undergo karyokinesis and then cytokinesis. Some cells, however, such as cardiomyocytes and hepatocytes, can produce binucleate cells by going through mitosis without cytoki...
Citation: BMC Developmental Biology 2014 14:46
The development of the craniofacial skeleton from embryonic mesenchyme is a complex process that is not yet completely understood, particularly for intramembranous bones. This study investigates the developmen...
Citation: BMC Developmental Biology 2014 14:44
Regulation of organ and body size is a fundamental biological phenomenon, requiring tight coordination between multiple tissues to ensure accurate proportional growth. In C. elegans, a TGF-β pathway is the major ...
Citation: BMC Developmental Biology 2014 14:43
The mechanistic target of rapamycin complex1 (mTORC1) signaling pathway has been implicated in functions of multicellular processes, including cell growth and metabolism. Although recent reports showed that ma...
Citation: BMC Developmental Biology 2014 14:42
The homeodomain transcription factor orthopedia (Otp) is an evolutionarily conserved regulator of neuronal fates. In vertebrates, Otp is necessary for the proper development of different regions of the brain a...
Citation: BMC Developmental Biology 2014 14:41
The sub-cortical maternal complex (SCMC), located in the subcortex of mouse oocytes and preimplantation embryos, is composed of at least four proteins encoded by maternal effect genes: OOEP, NLRP5/MATER, TLE6 ...
Citation: BMC Developmental Biology 2014 14:40
Citation: BMC Developmental Biology 2014 14:39
Hundreds of HSP40s derived from various species have been identified, of which several proteins are involved in spermatogenesis. DNAJB13 is a type II HSP40/DnaJ protein. In a previous study, we cloned mouse Dnajb...
Citation: BMC Developmental Biology 2014 14:38
Glandular organs require the development of a correctly patterned epithelial tree. These arise by iterative branching: early branches have a stereotyped anatomy, while subsequent branching is more flexible, br...
Citation: BMC Developmental Biology 2014 14:35
The switch from cartilage template to bone during endochondral ossification of the growth plate requires a dynamic and close interaction between cartilage and the developing vasculature. Vascular invasion of t...
Citation: BMC Developmental Biology 2014 14:36
Members of the Semaphorin 3 family (Sema3s) influence the development of the central nervous system, and some are implicated in regulating aspects of visual system development. However, we lack information abo...
Citation: BMC Developmental Biology 2014 14:34
Citation Impact
2.000 - 2-year Impact Factor
2.643 - 5-year Impact Factor
0.788 - Source Normalized Impact per Paper (SNIP)
1.109 - SCImago Journal Rank (SJR)
Usage
273,615 Downloads
203 Altmetric Mentions