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BMC Developmental Biology

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  1. Content type: Research article

    It has been found that microRNAs (miRNAs) play important roles in the regulation of tooth development, and most likely increase the complexity of the genetic network, thus lead to greater complexity of teeth. ...

    Authors: Ang Li, Ye Li, Tieli Song, Fu Wang, Dayong Liu, Zhipeng Fan, San Cheng, Chunmei Zhang, Jinsong Wang, Junqi He and Songlin Wang

    Citation: BMC Developmental Biology 2015 15:51

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  2. Content type: Research article

    This study describes the generation and analysis of the transcriptional profile of bovine inner cell mass (ICM) and trophectoderm (TE), obtained from in vivo developed embryos by using a bovine-embryo specific...

    Authors: S. M. Hosseini, I. Dufort, J. Caballero, F. Moulavi, H. R. Ghanaei and M. A. Sirard

    Citation: BMC Developmental Biology 2015 15:49

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  3. Content type: Research article

    Salamanders regenerate their tails after amputation anywhere along their length. How the system faithfully reconstitutes the original number of segments and length is not yet known.

    Authors: Carr D. Vincent, Fabian Rost, Wouter Masselink, Lutz Brusch and Elly M. Tanaka

    Citation: BMC Developmental Biology 2015 15:48

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  4. Content type: Research article

    Biliary atresia (BA) is a human infant disease with inflammatory fibrous obstructions in the bile ducts and is the most common cause for pediatric liver transplantation. In contrast, the sea lamprey undergoes ...

    Authors: Yu-Wen Chung-Davidson, Chu-Yin Yeh, Ugo Bussy, Ke Li, Peter J. Davidson, Kaben G. Nanlohy, C. Titus Brown, Steven Whyard and Weiming Li

    Citation: BMC Developmental Biology 2015 15:47

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  5. Content type: Methodology article

    Super-resolution fluorescence microscopy performed via 3D structured illumination microscopy (3D-SIM) is well established on flat, adherent cells. However, blastomeres of mammalian embryos are non-adherent, ro...

    Authors: Jens Popken, Maik Dahlhoff, Tuna Guengoer, Eckhard Wolf and Valeri Zakhartchenko

    Citation: BMC Developmental Biology 2015 15:46

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  6. Content type: Research article

    The endogenous ability to dedifferentiate, re-pattern, and re-differentiate adult cells to repair or replace damaged or missing structures is exclusive to only a few tetrapod species. The Mexican axolotl is on...

    Authors: Catherine D. McCusker, Antony Athippozhy, Carlos Diaz-Castillo, Charless Fowlkes, David M. Gardiner and S. Randal Voss

    Citation: BMC Developmental Biology 2015 15:45

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  8. Content type: Research article

    Acute kidney injury in mammals, which is caused by cardiovascular diseases or the administration of antibiotics with nephrotoxic side-effects is a life-threatening disease, since loss of nephrons is irreversib...

    Authors: Beate Hoppe, Stefan Pietsch, Martin Franke, Sven Engel, Marco Groth, Matthias Platzer and Christoph Englert

    Citation: BMC Developmental Biology 2015 15:43

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  9. Content type: Research article

    The investigation of skeletal muscle development is of importance in stock farming and biomedicine. It is still ambiguous that whether animals are born with the full set of skeletal muscle fibers or if the num...

    Authors: Mingsen Li, Xingyu Zhou, Yaosheng Chen, Yaping Nie, Huaxing Huang, Hu Chen and Delin Mo

    Citation: BMC Developmental Biology 2015 15:42

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  11. Content type: Research article

    TALE-class homeodomain transcription factors Meis and Pbx play important roles in formation of the embryonic brain, eye, heart, cartilage or hematopoiesis. Loss-of-function studies of Pbx1, 2 and 3 and Meis1 d...

    Authors: Ondrej Machon, Jan Masek, Olga Machonova, Stefan Krauss and Zbynek Kozmik

    Citation: BMC Developmental Biology 2015 15:40

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  12. Content type: Methodology article

    Components of the limb musculoskeletal system have distinct mesoderm origins. Limb skeletal muscles originate from somites, while the skeleton and attachments (tendons and connective tissues) derive from limb ...

    Authors: Adeline Bourgeois, Joana Esteves de Lima, Benjamin Charvet, Koichi Kawakami, Sigmar Stricker and Delphine Duprez

    Citation: BMC Developmental Biology 2015 15:39

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  13. Content type: Methodology article

    The GATA-binding factor 6 (Gata6) gene encodes a zinc finger transcription factor that often functions as a key regulator of lineage specification during development. It is the earliest known marker of the primit...

    Authors: Laina Freyer, Christian Schröter, Néstor Saiz, Nadine Schrode, Sonja Nowotschin, Alfonso Martinez-Arias and Anna-Katerina Hadjantonakis

    Citation: BMC Developmental Biology 2015 15:38

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  14. Content type: Research article

    Primitive endoderm is a cell lineage segregated from the epiblast in the blastocyst and gives rise to parietal and visceral endoderm. Sox7 is a member of the SoxF gene family that is specifically expressed in pri...

    Authors: Masaki Kinoshita, Daisuke Shimosato, Mariko Yamane and Hitoshi Niwa

    Citation: BMC Developmental Biology 2015 15:37

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  15. Content type: Research article

    Development of the valves and septa of the heart depends on the formation and remodeling of the endocardial cushions in the atrioventricular canal and outflow tract. These cushions are populated by mesenchyme ...

    Authors: Ryan J. Coram, Samantha J. Stillwagon, Anuradha Guggilam, Michael W. Jenkins, Maurice S. Swanson and Andrea N. Ladd

    Citation: BMC Developmental Biology 2015 15:36

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  16. Content type: Research article

    Pluripotent cells are present in early embryos until the levels of the pluripotency regulator Oct4 drop at the beginning of somitogenesis. Elevating Oct4 levels in explanted post-pluripotent cells in vitro res...

    Authors: Constantinos Economou, Anestis Tsakiridis, Filip J. Wymeersch, Sabrina Gordon-Keylock, Robert E Dewhurst, Dawn Fisher, Alexander Medvinsky, Andrew JH Smith and Valerie Wilson

    Citation: BMC Developmental Biology 2015 15:35

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  17. Content type: Research article

    Sex determination in mammals requires expression of the Y-linked gene Sry in the bipotential genital ridges of the XY embryo. Even minor delay of the onset of Sry expression can result in XY sex reversal, highlig...

    Authors: Christian Larney, Timothy L. Bailey and Peter Koopman

    Citation: BMC Developmental Biology 2015 15:34

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  18. Content type: Research article

    In multiple vertebrate organisms, including chick, Xenopus, and zebrafish, Fibroblast Growth Factor (FGF) and Wnt signaling cooperate during formation of the otic placode. However, in the mouse, although FGF sign...

    Authors: Kevin D. Wright, Amanda A. Mahoney Rogers, Jian Zhang and Katherine Shim

    Citation: BMC Developmental Biology 2015 15:33

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  19. Content type: Commentary

    Recent studies have identified epithelial stem and progenitor cell populations of the lung. We are just beginning to understand the mechanisms that regulate their homeostatic, regenerative and maladaptive beha...

    Authors: Matt L. Donne, Andrew J. Lechner and Jason R. Rock

    Citation: BMC Developmental Biology 2015 15:32

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  20. Content type: Research article

    It remains unclear to what extent midgut rotation determines human intestinal topography and pathology. We reinvestigated the midgut during its looping and herniation phases of development, using novel 3D visu...

    Authors: Jelly HM Soffers, Jill PJM Hikspoors, Hayelom K. Mekonen, S. Eleonore Koehler and Wouter H. Lamers

    Citation: BMC Developmental Biology 2015 15:31

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  21. Content type: Research article

    Nearly half of all individuals with Down Syndrome (DS) have some type of congenital heart defect (CHD), suggesting that DS sensitizes to CHD but does not cause it. We used a common mouse model of DS, the Ts65D...

    Authors: Renita C. Polk, Peter Gergics, Jeffrey D. Steimle, Huiqing Li, Ivan P. Moskowitz, Sally A. Camper and Roger H. Reeves

    Citation: BMC Developmental Biology 2015 15:30

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  22. Content type: Research article

    Magnetic resonance imaging (MRI) has many advantages in the research of in vivo embryonic brain development, specifically its noninvasive aspects and ability to avoid skeletal interference. However, few studie...

    Authors: Zien Zhou, Zengai Chen, Jiehui Shan, Weiwei Ma, Lei Li, Jinyan Zu and Jianrong Xu

    Citation: BMC Developmental Biology 2015 15:29

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  24. Content type: Research article

    Haploinsufficiency of the FOXL2 transcription factor in humans causes Blepharophimosis/Ptosis/Epicanthus Inversus syndrome (BPES), characterized by eyelid anomalies and premature ovarian failure. Mice lacking Fox...

    Authors: Mara Marongiu, Loredana Marcia, Emanuele Pelosi, Mario Lovicu, Manila Deiana, Yonqing Zhang, Alessandro Puddu, Angela Loi, Manuela Uda, Antonino Forabosco, David Schlessinger and Laura Crisponi

    Citation: BMC Developmental Biology 2015 15:27

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  25. Content type: Methodology article

    During the fourth larval (L4) stage, vulval cells of C. elegans undergo extensive morphogenesis accompanied by changes in gene expression. This phase of vulval development, occurring after the well-studied induct...

    Authors: Darren Z. L. Mok, Paul W. Sternberg and Takao Inoue

    Citation: BMC Developmental Biology 2015 15:26

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BMC Developmental Biology

ISSN: 1471-213X

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