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Page 10 of 21

  1. Presence of all three ParaHox genes has been described in deuterostomes and lophotrochozoans, but to date one of these three genes, Xlox has not been reported from any ecdysozoan taxa and both Xlox and Gsx are ab...

    Authors: Leyli Samadi and Gerhard Steiner
    Citation: BMC Developmental Biology 2010 10:74
  2. Male Irs2-/- mice develop fatal type 2 diabetes at 13-14 weeks. Defects in neuronal proliferation, pituitary development and photoreceptor cell survival manifest in Irs2-/- mice. We identify retarded renal growth...

    Authors: Rosemarie M Carew, Marianna Sadagurski, Roel Goldschmeding, Finian Martin, Morris F White and Derek P Brazil
    Citation: BMC Developmental Biology 2010 10:73
  3. In vivo studies demonstrate that the Prox1 transcription factor plays a critical role in the development of the early lymphatic system. Upon Prox1 expression, early lymphatic endothelial cells differentiate from ...

    Authors: Harold Kim, Vicky PKH Nguyen, Tatiana V Petrova, Maribelle Cruz, Kari Alitalo and Daniel J Dumont
    Citation: BMC Developmental Biology 2010 10:72
  4. Inhibitors-of-Apoptosis-Proteins (IAPs) are an evolutionarily conserved family of proteins capable of regulating several facets of apoptosis. IAPs are frequently dysregulated in cancer, but their role in the r...

    Authors: Thomas W Owens, Fiona M Foster, Jolanta Tanianis-Hughes, Julia Y Cheung, Lisa Brackenbury and Charles H Streuli
    Citation: BMC Developmental Biology 2010 10:71
  5. It is well established that the immature myocardium preferentially utilises non-oxidative energy-generating pathways. It exhibits low energy-transfer capacity via the creatine kinase (CK) shuttle, reflected in...

    Authors: Alexandra Fischer, Michiel ten Hove, Liam Sebag-Montefiore, Helga Wagner, Kieran Clarke, Hugh Watkins, Craig A Lygate and Stefan Neubauer
    Citation: BMC Developmental Biology 2010 10:70
  6. Transforming growth factor β proteins (Tgfβs) are secreted cytokines with well-defined functions in the differentiation of the musculoskeletal system of the developing limb. Here we have studied in chicken emb...

    Authors: Carlos I Lorda-Diez, Juan A Montero, Juan A Garcia-Porrero and Juan M Hurle
    Citation: BMC Developmental Biology 2010 10:69
  7. Mammals and Drosophila melanogaster share some striking similarities in spermatogenesis. Mitochondria in spermatids undergo dramatic morphological changes and syncytial spermatids are stripped from their cytoplas...

    Authors: Christoph Metzendorf and Maria I Lind
    Citation: BMC Developmental Biology 2010 10:68
  8. Outer dense fiber protein 2, Odf2, is a major component of the outer dense fibers, ODF, in the flagellum of spermatozoa. ODF are associated with microtubule doublets that form the axoneme. We recently demonstr...

    Authors: Heide Tarnasky, Min Cheng, Young Ou, Jacob C Thundathil, Richard Oko and Frans A van der Hoorn
    Citation: BMC Developmental Biology 2010 10:67
  9. The synthesis of microRNA (miRNA) is a multi-step process that requires the action of the ribonuclease Dicer1. Dicer1 is responsible for the final processing of miRNA and has been implicated in cellular proces...

    Authors: Chen-Che J Huang and Humphrey HC Yao
    Citation: BMC Developmental Biology 2010 10:66
  10. In metazoans, the hematopoietic system plays a key role both in normal development and in defense of the organism. In Drosophila, the cellular immune response involves three types of blood cells: plasmatocytes...

    Authors: Amélie Avet-Rochex, Karène Boyer, Cédric Polesello, Vanessa Gobert, Dani Osman, Fernando Roch, Benoit Augé, Jennifer Zanet, Marc Haenlin and Lucas Waltzer
    Citation: BMC Developmental Biology 2010 10:65
  11. Nuclear transfer has the potential to become one strategy for fish genetic resources management, by allowing fish reconstruction from cryopreserved somatic cells. Survival rates after nuclear transfer are stil...

    Authors: Pierre-Yves Le Bail, Alexandra Depince, Nathalie Chenais, Sophie Mahe, Gerard Maisse and Catherine Labbe
    Citation: BMC Developmental Biology 2010 10:64
  12. Caste differentiation in social insects is a type of polyphenism that enables division of labor among members of a colony. This elaborate social integration has attracted broad interest, although little is kno...

    Authors: Shigeyuki Koshikawa, Richard Cornette, Tadao Matsumoto and Toru Miura
    Citation: BMC Developmental Biology 2010 10:63
  13. Articular cartilage (AC) is the layer of tissue that covers the articulating ends of the bones in diarthrodial joints. Across species, adult AC shows an arcade-like structure with collagen predominantly perpen...

    Authors: Mark C van Turnhout, Henk Schipper, Bas Engel, Willem Buist, Sander Kranenbarg and Johan L van Leeuwen
    Citation: BMC Developmental Biology 2010 10:62
  14. Bone morphogenetic proteins (BMPs) are members of the conserved transforming growth factor β (TGFβ superfamily, and play many developmental and homeostatic roles. In C. elegans, a BMP-like pathway, the DBL-1 path...

    Authors: Andrew F Roberts, Tina L Gumienny, Ryan J Gleason, Huang Wang and Richard W Padgett
    Citation: BMC Developmental Biology 2010 10:61
  15. To maintain pluripotency of human embryonic stem (huES) cells in feeder-free culture it has been necessary to provide a Matrigel substratum, which is a complex of poorly defined extracellular matrices and grow...

    Authors: Masato Nagaoka, Karim Si-Tayeb, Toshihiro Akaike and Stephen A Duncan
    Citation: BMC Developmental Biology 2010 10:60
  16. Copines are calcium-dependent phospholipid-binding proteins found in diverse eukaryotic organisms. We are studying the function of copines in Dictyostelium discoideum, a single-celled amoeba that undergoes cell d...

    Authors: Tasha S Smith, Jaimie M Pineda, Alex C Donaghy and Cynthia K Damer
    Citation: BMC Developmental Biology 2010 10:59
  17. The development of teeth is the result of interactions between competent mesenchyme and epithelium, both of which undergo extensive morphogenesis. The importance of cell adhesion molecules in morphogenesis has...

    Authors: Barbara Verstraeten, Ellen Sanders, Jolanda van Hengel and Ann Huysseune
    Citation: BMC Developmental Biology 2010 10:58
  18. Our understanding of the mechanisms that protect the developing embryo from intrauterine stress is limited. Recently, adenosine has been demonstrated to play a critical role in protecting the embryo against hy...

    Authors: Christopher C Wendler, Ryan R Poulsen, Satish Ghatpande, Robert W Greene and Scott A Rivkees
    Citation: BMC Developmental Biology 2010 10:57
  19. Three kidney systems appear during vertebrate development: the pronephroi, mesonephroi and metanephroi. The pronephric duct is the first or primary ureter of these kidney systems. Its role as a key player in t...

    Authors: Birgitte M Haugan, Kenneth A Halberg, Åse Jespersen, Lea R Prehn and Nadja Møbjerg
    Citation: BMC Developmental Biology 2010 10:56
  20. Teneurins are transmembrane proteins that assist morphogenetic processes in many organisms. ten-1 is the C. elegans teneurin homolog with two transcripts, ten-1a and ten-1b, that respectively encode a long (TEN-1...

    Authors: Catarina Mörck, Vivekanand Vivekanand, Gholamali Jafari and Marc Pilon
    Citation: BMC Developmental Biology 2010 10:55
  21. Vertebrates show clear asymmetry in left-right (L-R) patterning of their organs and associated vasculature. During mammalian development a cilia driven leftwards flow of liquid leads to the left-sided expressi...

    Authors: Jonathan Stevens, Alexander Ermakov, Jose Braganca, Helen Hilton, Peter Underhill, Shoumo Bhattacharya, Nigel A Brown and Dominic P Norris
    Citation: BMC Developmental Biology 2010 10:54
  22. The red flour beetle Tribolium castaneum has developed into an insect model system second only to Drosophila. Moreover, as a coleopteran it represents the most species-rich metazoan taxon which also includes many...

    Authors: Johannes B Schinko, Markus Weber, Ivana Viktorinova, Alexandros Kiupakis, Michalis Averof, Martin Klingler, Ernst A Wimmer and Gregor Bucher
    Citation: BMC Developmental Biology 2010 10:53
  23. The neural crest is a group of multipotent cells that emerges after an epithelial-to-mesenchymal transition from the dorsal neural tube early during development. These cells then migrate throughout the embryo,...

    Authors: Michelle Reyes, Katrina Zandberg, Iska Desmawati and Maria E de Bellard
    Citation: BMC Developmental Biology 2010 10:52
  24. Several imprinted genes have been implicated in the process of placentation. The distal region of mouse chromosome 7 (Chr 7) contains at least ten imprinted genes, several of which are expressed from the mater...

    Authors: Rosemary Oh-McGinnis, Aaron B Bogutz, Kang Yun Lee, Michael J Higgins and Louis Lefebvre
    Citation: BMC Developmental Biology 2010 10:50
  25. Growth factors and their receptors are mediators of organogenesis and must be tightly regulated in a temporal and spatial manner for proper tissue morphogenesis. Intracellular regulators of growth factor signa...

    Authors: Xuehui Yang, Sean Kilgallen, Viktoria Andreeva, Douglas B Spicer, Ilka Pinz and Robert Friesel
    Citation: BMC Developmental Biology 2010 10:48
  26. Adipocyte hyperplasia is associated with obesity and arises due to adipogenic differentiation of resident multipotent stem cells in the vascular stroma of adipose tissue and remote stem cells of other organs. ...

    Authors: Shu-Wen Qian, Xi Li, You-You Zhang, Hai-Yan Huang, Yuan Liu, Xia Sun and Qi-Qun Tang
    Citation: BMC Developmental Biology 2010 10:47
  27. The C. elegans gene folt-1 is an ortholog of the human reduced folate carrier gene. The FOLT-1 protein has been shown to transport folate and to be involved in uptake of exogenous folate by worms. A knockout muta...

    Authors: Misa U Austin, Wei-Siang Liau, Krishnaswamy Balamurugan, Balasubramaniem Ashokkumar, Hamid M Said and Craig W LaMunyon
    Citation: BMC Developmental Biology 2010 10:46
  28. Numerous cases of predator-induced polyphenisms, in which alternate phenotypes are produced in response to extrinsic stimuli, have been reported in aquatic taxa to date. The genus Daphnia (Branchiopoda, Cladocera...

    Authors: Hitoshi Miyakawa, Maki Imai, Naoki Sugimoto, Yuki Ishikawa, Asano Ishikawa, Hidehiko Ishigaki, Yasukazu Okada, Satoshi Miyazaki, Shigeyuki Koshikawa, Richard Cornette and Toru Miura
    Citation: BMC Developmental Biology 2010 10:45
  29. The zinc-finger transcription factor GLI3 is an important mediator of Sonic hedgehog signaling and crucial for patterning of many aspects of the vertebrate body plan. In vertebrates, the mechanism of SHH signa...

    Authors: Amir A Abbasi, Zissis Paparidis, Sajid Malik, Fiona Bangs, Ansgar Schmidt, Sabine Koch, Javier Lopez-Rios and Karl-Heinz Grzeschik
    Citation: BMC Developmental Biology 2010 10:44
  30. Red algae are primitive photosynthetic eukaryotes, whose spores are ideal subjects for studies of photosynthesis and development. Although the development of red alga spores has received considerable research ...

    Authors: Xiujun Xie, Guangce Wang, Guanghua Pan, Shan Gao, Pu Xu and Jianyi Zhu
    Citation: BMC Developmental Biology 2010 10:43
  31. Many species form extraembryonic tissues during embryogenesis, such as the placenta of humans and other viviparous mammals. Extraembryonic tissues have various roles in protecting, nourishing and patterning em...

    Authors: Sung-Kook Hong, Carly S Levin, Jamie L Brown, Haiyan Wan, Brad T Sherman, Da Wei Huang, Richard A Lempicki and Benjamin Feldman
    Citation: BMC Developmental Biology 2010 10:42
  32. The transcription factor Pax6 functions in the specification and maintenance of the differentiated cell lineages in the endocrine pancreas. It has two DNA binding domains, the paired domain and the homeodomain...

    Authors: Petra Dames, Ramona Puff, Michaela Weise, Klaus G Parhofer, Burkhard Göke, Magdalena Götz, Jochen Graw, Jack Favor and Andreas Lechner
    Citation: BMC Developmental Biology 2010 10:39
  33. The C-terminal Eps15 homology domain-containing protein 1 (EHD1) is ubiquitously expressed and regulates the endocytic trafficking and recycling of membrane components and several transmembrane receptors. To e...

    Authors: Mark A Rainey, Manju George, GuoGuang Ying, Reiko Akakura, Daniel J Burgess, Ed Siefker, Tom Bargar, Lynn Doglio, Susan E Crawford, Gordon L Todd, Venkatesh Govindarajan, Rex A Hess, Vimla Band, Mayumi Naramura and Hamid Band
    Citation: BMC Developmental Biology 2010 10:37
  34. Six3a belongs to the SIX family of homeodomain proteins and is expressed in the most anterior neural plate at the beginning of neurogenesis in various species. Though the function of Six3a as a crucial regulat...

    Authors: Chung-Hao Chao, Horng-Dar Wang and Chiou-Hwa Yuh
    Citation: BMC Developmental Biology 2010 10:35
  35. Pattern formation of the limb skeleton is regulated by a complex interplay of signaling centers located in the ectodermal sheath and mesenchymal core of the limb anlagen, which results, in the forelimb, in the...

    Authors: Poongodi Geetha-Loganathan, Suresh Nimmagadda, Bodo Christ, Ruijin Huang and Martin Scaal
    Citation: BMC Developmental Biology 2010 10:32
  36. The interaction between the karyoplast and cytoplast plays an important role in the efficiency of somatic cell nuclear transfer (SCNT), but the underlying mechanism remains unclear. It is generally accepted th...

    Authors: Zhong-hai Yan, Yi-ye Zhou, Jing Fu, Fei Jiao, Lei-wen Zhao, Peng-fei Guan, Shu-zhen Huang, Yi-tao Zeng and Fanyi Zeng
    Citation: BMC Developmental Biology 2010 10:31
  37. Endogenous peptides such as neuropeptides are involved in numerous biological processes in the fully developed brain but very little is known about their role in brain development. Japanese quail is a commonly...

    Authors: Birger Scholz, Henrik Alm, Anna Mattsson, Anna Nilsson, Kim Kultima, Mikhail M Savitski, Maria Fälth, Karl Sköld, Björn Brunström, Per E Andren and Lennart Dencker
    Citation: BMC Developmental Biology 2010 10:30
  38. Very little is known about how intervertebral disc (IVD) is formed or maintained. Members of the TGF-β superfamily are secreted signaling proteins that regulate many aspects of development including cellular d...

    Authors: Philip Sohn, Megan Cox, Dongquan Chen and Rosa Serra
    Citation: BMC Developmental Biology 2010 10:29
  39. Cloning of cattle by somatic cell nuclear transfer (SCNT) is associated with a high incidence of pregnancy failure characterized by abnormal placental and foetal development. These abnormalities are thought to...

    Authors: Christine Couldrey and Rita SF Lee
    Citation: BMC Developmental Biology 2010 10:27
  40. Regulatory elements that control expression of specific genes during development have been shown in many cases to contain functionally-conserved modules that can be transferred between species and direct gene ...

    Authors: Michael J McGrew, Adrian Sherman, Simon G Lillico, Lorna Taylor and Helen Sang
    Citation: BMC Developmental Biology 2010 10:26