Figure 4
From: Fertilization in C. elegans requires an intact C-terminal RING finger in sperm protein SPE-42
C. elegans / C. briggsae chimeric constructs. (A) Pair-wise comparison of C. elegans and C. briggsae SPE-42 proteins showing the striking divergence between the two proteins at the C-terminus. The divergent sequence corresponds exactly to the 3'-most exon of each gene. Solid lines above the sequence indicate membrane-spanning domains. (B) Chimeric constructs were made to determine the effect of the divergent sequence on protein function. All four constructs are under the control of the C. elegans spe-42 promoter and 3' UTR.