From: The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits
Items | Group | R-MSE | P-value | |||
---|---|---|---|---|---|---|
Control | HBAD-GFP | HBAD-ocu-miR-205-GFP | HBAD-ocu-miR-205-5p-sponge-GFP | |||
Proliferation of dermal papilla cells | ||||||
 Optical density (OD) value | 0.56 ± 0.01b | 0.55 ± 0.01b | 0.61 ± 0.01a | 0.34 ± 0.01c | 0.0356 | < 0.0001 |
Cell cycle of dermal papilla cells | ||||||
 Resting state/first gap (G0/G1) | 87.79 ± 1.00a | 84.68 ± 1.01b | 77.71 ± 0.88c | 85.57 ± 1.03ab | 2.7795 | < 0.0001 |
 Synthesis (S) | 7.15 ± 0.85b | 9.48 ± 0.95b | 14.73 ± 0.62a | 8.97 ± 0.68b | 2.2232 | < 0.0001 |
 Second gap/mitosis (G2/M) | 5.07 ± 0.24b | 5.37 ± 0.49b | 7.56 ± 0.37a | 5.46 ± 0.35b | 1.0523 | 0.0002 |
Apoptosis of dermal papilla cells | ||||||
 Early apoptotic ratio (Q4) | 33.95 ± 0.40b | 32.86 ± 1.04b | 36.71 ± 0.67a | 29.16 ± 0.47c | 1.9470 | < 0.0001 |
 Later apoptotic ratio (Q2) | 33.46 ± 0.57b | 32.15 ± 1.33b | 36.11 ± 0.73a | 31.40 ± 0.57b | 2.4323 | 0.0032 |
 Total apoptosis ratio (Q4 + Q2) | 67.41 ± 0.51b | 65.01 ± 1.50b | 72.83 ± 1.14a | 60.56 ± 0.47 b | 2.8310 | < 0.0001 |