Fig. 4
From: Short term optical defocus perturbs normal developmental shifts in retina/RPE protein abundance
Pathway enrichment in mitochondrial protein import, rab GTPase, and integration of energy metabolism clusters. a Bubble plot illustrating the NES and FDR across all pairwise comparisons for the four enriched pathways in the ‘mitochondrial protein import’, rab GTPase and ‘integration of energy metabolism’ clusters. Statistically significant enrichments (FDR < 0.05) are shown as filled circles. Heat maps show the mean LQF intensity across lens conditions for all LES proteins contributing to the enrichment of one or more pathways in the b mitochondrial protein import, c rab GTPase and d integration of energy metabolism clusters