Fig. 1
From: Short term optical defocus perturbs normal developmental shifts in retina/RPE protein abundance
Pathway enrichment in the nucleocytoplasmic transport cluster. a Bubble plot illustrating the normalized enrichment score (NES) and false discovery rate (FDR) across all pairwise comparisons for the thirty-eight enriched pathways in the ‘nucleocytoplasmic transport’ cluster. Statistically significant enrichments (FDR < 0.05) are shown as filled circles. b Heat map showing the mean label-free quantification (LFQ) intensity across lens conditions for all leading edge subset (LES) proteins contributing to the enrichment of one or more nucleocytoplasmic pathways. Note that the LES varied across pathways that were significantly enriched over time in both positive and no lens conditions. Full details of the LES for each comparison are provided in, Additional file 4 Figure S3