Fig. 5

Comparison of percentage of tauGFP-positive cells and corrected stripe number in mosaic adrenal cortices from four groups of tauGFP transgenic mice. a TgTP6.3 ^Tg/− mosaic adrenal cortices had a higher mean percentage of tauGFP-positive cells than TgTP6.4 ^Tg/− mosaic cortices and, for males, this was significant by Kruskal-Wallis (KW) tests and Dunn’s multiple comparison post-tests. There were no significant differences between males and females of the same genotype. The mean percentages of tauGFP-positive cells (±95% CI) were: TgTP6.3 ^Tg/− females, 81.1 ± 12.4%; TgTP6.4 ^Tg/− females, 38.5 ± 13.1%; TgTP6.3 ^Tg/− males, 91.0 ± 3.3%; TgTP6.4 ^Tg/− males, 37.7 ± 14.7%. b There were no significant differences in corrected stripe numbers in mosaic adrenal cortices among any of the four groups of mice (both sexes for two genotypes) by 2-way ANOVA and Bonferroni’s multiple comparison post-tests. The mean corrected stripe numbers (±95% CI) were: TgTP6.3 ^Tg/− females, 44.1 ± 12.8; TgTP6.4 ^Tg/− females, 50.8 ± 9.5; TgTP6.3 ^Tg/− males, 60.5 ± 12.2; TgTP6.4 ^Tg/− males, 57.0 ± 7.2. The box and whisker plots show the median (horizontal line within the box), upper and lower quartiles (top and bottom of boxes), and the minimum and maximum of all the data (ends of whiskers). ***P < 0.001. The number of adrenal glands in each group is shown within or above the box and whiskers; one adrenal gland was analysed per mouse