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Fig. 6 | BMC Developmental Biology

Fig. 6

From: BMP-SMAD signalling output is highly regionalized in cardiovascular and lymphatic endothelial networks

Fig. 6

BRE::gfp transcriptional activity in postnatal blood and lymphatic vessels. a Stitch of a P4 mesentery with immunodetection of GFP and the pan-endothelial marker CD31. Arteries, veins and collecting lymphatic vessels in a P6 (b) and P10 (c) mesentery are depicted. Arrows point to GFP-positive peri-endothelial cells. Arrowheads show GFP-positive ECs in the vicinity of a valve. Sections of P6 intestines with immunodetection of GFP and Endomucin (d) or the lymphatic vessel marker LYVE1 (e). White arrows point to some GFP-positive cells in a capillary, yellow arrows show GFP-positive LECs in a lacteal. Arrowheads show some GFP-positive goblet cells. Stitch of P6 (f) and P10 (g) dorsal ear skin with immunodetection of GFP and the lymphatic marker Podoplanin. GFP-positive LECs at the branch points are depicted by arrows at P6 (h) and P10 (i). A: artery; L: lymphatic vessel; V: vein. Scale bars: 1 mm (a); 500 μm (f–g); 75 μm (b–e; h–i)

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