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Table 3 A selection of proteins that associate with the Mef2c gene

From: BRG1 interacts with GLI2 and binds Mef2c gene in a hedgehog signalling dependent manner during in vitro cardiomyogenesis

Protein Mef2c domain Target Sequencea Location (mm10: Chr 13) Source of Protein Referencesb
BRG1 - - 83.504,012 - 83,504,138 Mouse [84]
MEF2C MADS-box acctttacagCTAAATTTACtccagagtg 83,504,087 - 83,504,115 Mouse [94]
MyoD E-box gagtgacatgaaCAGGTGcaccctggcct 83,504,111 - 83,504,139 Mouse [94]
E12 E-box gagtgacatgaaCAGGTGcaccctggcct 83,504,111 - 83,504,139 Mouse [94]
GATA-4 GATA-d taagagttcTTATCAgtgtc 83,523,287 - 83,523,306 Rat [82]
GATA-p gtcacccgctatCTATCGgtcagg 83,523,351 - 83,523,374
ISL-1 ISL-d gtcaggggagcCTAATGcatttgggaa 83,523,369 - 83,523,395 Hamster [82]
ISL-p ggtttacttgCTAATGacctggataa 83,523,405 - 83,523,430
SOX10 SOX gaatgcactgacTACAAAGtgcatcctgaag 83,565,883 - 83,565,913 Mouse [96]
Binding ggccatttagctCACAATGaaggtctgtgtt 83,565,913 - 83,565,943
Site aaatagctctatAACAAAGtaactacagagt 83,565,947 - 83,565,977
ETS1 ETS-A agttactcTCTTCCTGttatgaca 83,582,754 - 83,582,777 Mammalian [97, 98]
ETV2 ETS-A agttactcTCTTCCTGttatgaca 83,582,754 - 83,582,777 Mammalian [97]
FOXC1 FOX-NC ggaagttactctcttccTGTTATGacaggaaagcgtagaca 83,582,752 - 83,582,791 Mouse [97]
FOXC2 FOX-NC ggaagttactctcttccTGTTATGacaggaaagcgtagaca 83,582,752 - 83,582,791 Mouse [97]
FOXO1 FOX-NC ggaagttactctcttccTGTTATGacaggaaagcgtagaca 83,582,752 - 83,582,791 Mouse [97]
  1. Chr Chromosome
  2. aUppercase nucleotides in the target sequence represent nonconsensus binding domains
  3. bAll binding site information for proteins, except BRG1 and SOX10, were compiled with information gathered through TRANSFAC