BRG1 interacts with GLI2 and binds Mef2c gene in a hedgehog signalling dependent manner during in vitro cardiomyogenesis

Table 3 A selection of proteins that associate with the Mef2c gene

Protein	Mef2c domain	Target Sequence^a	Location (mm10: Chr 13)	Source of Protein	References^b
BRG1	-	-	83.504,012 - 83,504,138	Mouse	[84]
MEF2C	MADS-box	acctttacagCTAAATTTACtccagagtg	83,504,087 - 83,504,115	Mouse	[94]
MyoD	E-box	gagtgacatgaaCAGGTGcaccctggcct	83,504,111 - 83,504,139	Mouse	[94]
E12	E-box	gagtgacatgaaCAGGTGcaccctggcct	83,504,111 - 83,504,139	Mouse	[94]
GATA-4	GATA-d	taagagttcTTATCAgtgtc	83,523,287 - 83,523,306	Rat	[82]
GATA-4	GATA-p	gtcacccgctatCTATCGgtcagg	83,523,351 - 83,523,374	Rat	[82]
ISL-1	ISL-d	gtcaggggagcCTAATGcatttgggaa	83,523,369 - 83,523,395	Hamster	[82]
ISL-1	ISL-p	ggtttacttgCTAATGacctggataa	83,523,405 - 83,523,430	Hamster	[82]
SOX10	SOX	gaatgcactgacTACAAAGtgcatcctgaag	83,565,883 - 83,565,913	Mouse	[96]
	Binding	ggccatttagctCACAATGaaggtctgtgtt	83,565,913 - 83,565,943
	Site	aaatagctctatAACAAAGtaactacagagt	83,565,947 - 83,565,977
ETS1	ETS-A	agttactcTCTTCCTGttatgaca	83,582,754 - 83,582,777	Mammalian	[97, 98]
ETV2	ETS-A	agttactcTCTTCCTGttatgaca	83,582,754 - 83,582,777	Mammalian	[97]
FOXC1	FOX-NC	ggaagttactctcttccTGTTATGacaggaaagcgtagaca	83,582,752 - 83,582,791	Mouse	[97]
FOXC2	FOX-NC	ggaagttactctcttccTGTTATGacaggaaagcgtagaca	83,582,752 - 83,582,791	Mouse	[97]
FOXO1	FOX-NC	ggaagttactctcttccTGTTATGacaggaaagcgtagaca	83,582,752 - 83,582,791	Mouse	[97]

Chr Chromosome
^aUppercase nucleotides in the target sequence represent nonconsensus binding domains
^bAll binding site information for proteins, except BRG1 and SOX10, were compiled with information gathered through TRANSFAC

ISSN: 1471-213X