Fig. 1

Med12 mediates suppression of genes involved in “Cell Adhesion”. Functional gene interaction networks were identified by IPA®. Genes are represented as nodes, and the biological relationship between two nodes is represented as a line. The color of the node indicates up- or down- regulation (red, up; green, down); uncolored nodes represent genes that were not identified as differentially expressed in our microarray, but have nonetheless been integrated into the computationally generated networks on the basis of the evidence stored in the IPA knowledge memory indicating a relevance to this network