Fig. 1

Gene ontology (GO) analyses of liver transcriptomes in metamorphic land mark stages. X-axis represents the GO categories and Y-axis represents gene clusters (listed in Additional file 1). Color scale represents the Log₂ (transcript number in transcriptome 1/transcript number in transcriptome 2). Only genes with 2-fold changes (or greater) are shown. a Heat map showing GO categories at least 2-fold higher in larval (L) compared to metamorphic stage 2 (M2), p < 0.05, false discovery rate ≤ 0.1. b Heat map showing GO categories at least 2-fold higher in M2 compared to L, p < 0.05, false discovery rate ≤ 0.1. c Heat map showing GO categories at least 2-fold higher in metamorphic stage 5 (M5) compared to M2, p < 0.05, false discovery rate ≤ 0.1. d Heat map showing GO categories at least 2-fold higher in newly transformed juvenile (JV) compared to M5, p < 0.05, false discovery rate ≤ 0.1