Fig. 8
From: Meis2 is essential for cranial and cardiac neural crest development
Expression of NCC markers in the absence of Meis2. (a-a’) Pax3 immnostaining of trigeminal ganglions in systemic Meis2-/- E10.5 embryos showing greatly reduced or even absent ganglions V. (b-b’) Pax3 in the second pharyngeal arch (PA2). (c-c’) Tfap2 immunostaining in Meis2-/- embryos at E10.5. (d-d’) Sox10 immunofluorescence of ganglions V at E10.5. (e-e’) Melanocytes stained with anti-Mitf were detected normally in Meis2 nulls. (f-f’) Sox10 in dorsal root ganglia and the peripheral nervous system was not changed in mutants. DRG, dorsal root ganglia; H, hindbrain; V, trigeminal ganglion; PA2, the second pharyngeal arch;, sc, spinal cord