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Table 1 Reduced EGF signaling causes loss of ceh-13::GFP expression

From: The roles of EGF and Wnt signaling during patterning of the C. elegans Bγ/δ Equivalence Group

Genotypea

n

ceh-13::GFP b in Bγ (%)

Intact, wild type

41

100

Mock ablated, wild type

3

100

U-F-c, wild type

8

12.5***

let-60(rf)/Ras

42

57.1***

let-23(rf)/EGFR d

20

55***

sem-5(rf)/Grb-2

30

26.7***

  1. ***p < 0.0001; Fisher's Exact Test. The p values for all genotypes were calculated as compared to the Intact, wild-type genotype, except for U and F ablated wild-type males which were compared to mock ablated wild-type males.
  2. a The alleles used were let-23(sy97), let-60(n2021) and sem-5(n1619). All strains contained him-5(e1490).
  3. b All strains examined carried the integrated ceh-13::GFP transgene, syIs145.
  4. c F and U were ablated in these animals.
  5. d ceh-13::GFP expression was much dimmer as compared to wild-type expression in 7 of the 11 let-23(rf) males that had expression in γ.