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Figure 6 | BMC Developmental Biology

Figure 6

From: ERG is required for the differentiation of embryonic stem cells along the endothelial lineage

Figure 6

ERG target genes in VEGF-R2+ ES cells. (A) Normalized microarray expression values for ERG in VEGF-R2+ cells sorted from ERG shRNA or control cells 2, 3, and 4 days after differentiation. (B) Heat map of a subset of genes that are significantly differentially downregulated after 3 days and 4 days in ERG shRNA versus control ES cells. In the heatmaps, rows represent genes and columns represent samples, ordered as control and shRNA treated. Genes are clustered using row-normalized signal values which are mapped to the [-1,1] interval. Transcription factors are shown in blue. All other genes are shown in black. Signal values are color-coded so that red and green represent high and low expression values, respectively.

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