Figure 5
CAP-H and CAP-D2 are essential components of the condensin I complex. Morphant embryos show smaller heads and eyes. Transverse vibratome sections of embryonic retinae counterstained with phalloidin to visualize plexiform layers (red) and propidium iodide to mark nuclei (green). cap-h or cap-d2 morphant retinae are smaller in size. Similar to cap-gs105 mutant retinae, nuclei are aberrantly shaped and sized which is indicative of polyploidy/genomic imbalances. INL, inner nuclear layer; PRL, photoreceptor cell layer.