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Table 1 The developmental rates of somatic cell nuclear transfer (SCNT) embryos in the absence or presence of TSA.

From: Trichostatin A treatment of cloned mouse embryos improves constitutive heterochromatin remodeling as well as developmental potential to term

 

N° activated

N° at 2c (%)

N° transferred

N° live offspring (%)

N° 2c remaining in culture

N° at blastocyst (%)

SCNT Embryos

669

568 (85)

342

1 (0.3)

226

71 (31.4)

TSA-SCNT Embryos

387

319 (82.5)

193

6 (3.1)

126

44 (34.9)

  1. Statistical difference was calculated using Chi-square and was found to be significant for live offspring only (p-value < 0.01).