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Table 1 The developmental rates of somatic cell nuclear transfer (SCNT) embryos in the absence or presence of TSA.

From: Trichostatin A treatment of cloned mouse embryos improves constitutive heterochromatin remodeling as well as developmental potential to term

  N° activated N° at 2c (%) N° transferred N° live offspring (%) N° 2c remaining in culture N° at blastocyst (%)
SCNT Embryos 669 568 (85) 342 1 (0.3) 226 71 (31.4)
TSA-SCNT Embryos 387 319 (82.5) 193 6 (3.1) 126 44 (34.9)
  1. Statistical difference was calculated using Chi-square and was found to be significant for live offspring only (p-value < 0.01).