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Figure 9 | BMC Developmental Biology

Figure 9

From: Pax7 is requisite for maintenance of a subpopulation of superior collicular neurons and shows a diverging expression pattern to Pax3 during superior collicular development

Figure 9

A diagram detailing differential placement of separately generated populations of Pax7+ cells at P5. A diagram of Pax7+ cells in the superior colliculus of wildtype (a) and Pax7 mutant (b) mice at P5. Cells generated at E11 (red) and E13 (purple) show overlapping (medial) and unique (ventral [E11]/dorsal [E13]) expression patterns (a). We propose that cells generated at E13 show reduced capacity for long term maintenance in Pax7 mutant mice (b), generating a phenotype whereby a superficial region is absent of Pax7+ cells, and the region immediately ventral to this exhibits a reduction in the number of Pax7+ cells (refer Fig 2e). Abbrev. CC, cerebral cortex; IC, inferior colliculus.

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BMC Developmental Biology

ISSN: 1471-213X

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