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Table 1 pha-4 and daf-16 are required for dauer recovery

From: Function of the PHA-4/FOXA transcription factor during C. eleganspost-embryonic development

Genotype

RNAi

Dauer recovery (%) a

n b

p

pha-4is required for dauer recovery

daf-7(e1372)

control

97.9 ± 2.1

71

/

daf-7(e1372)

pha-4

32.1 ± 4.4

76

0.0002 c

daf-1(m40)

control

99.3 ± 0.7

89

/

daf-1(m40)

pha-4

27.4 ± 6.0

89

0.0003 c

daf-2(e1370)

control

96.0 ± 1.4

108

/

daf-2(e1370)

pha-4

10.4 ± 1.9

87

<0.0001 c

age-1(m865)

control

96.6 ± 1.9

86

/

age-1(m865)

pha-4

2.3 ± 1.2

84

<0.0001 c

daf-16 is required for dauer recovery

daf-7(e1372)

/

97.3 ± 1.3

78

/

daf-16(mgDf47); daf-7(e1372)

/

41.0 ± 3.6

92

0.0001 d

PHA-4 and DAF-16 function in parallel during dauer recovery

daf-7(e1372)

control

97.3 ± 1.5

111

/

daf-7(e1372)

pha-4

44.0 ± 2.4

107

<0.0001 c

daf-16(mgDf47); daf-7(e1372)

control

53.5 ± 6.2

109

0.0023 e

daf-16(mgDf47); daf-7(e1372)

pha-4

9.1 ± 2.1

101

0.0024 c

0.0004 f

  1. a Mean percentages of dauer recovery ± standard errors.
  2. b Number of animals scored.
  3. c Daf-c mutants treated with control RNAi vs. pha-4 RNAi; p values for t-tests were calculated using the GraphPad Prism 4 software..
  4. d daf-7 vs. daf-16; daf-7 treated with OP50 E. coli food.
  5. e daf-7 vs. daf-16, daf-7 treated with control RNAi.
  6. f daf-7 vs. daf-16; daf-7 with pha-4 RNAi.