Figure 5From: PITX2 gain-of-function induced defects in mouse forelimb developmentPITX2 is over-expressed in both right and left forelimbs of the Ktcn-PITX2 mice. (A and B) H&E stained sagittal paraffin sections of left and right forelimb from one individual E14.5 mouse. The marked areas are magnified in C and D. (C and D) Immunohistochemistry reveals PITX2 over-expression in both right and left forelimb. Scale bar: 0.5 mm.Back to article page