Figure 5

GABA concentration in amniotic fluid derived from pregnancies carrying an affected SSADH-deficient human fetus. Data are depicted as box and whiskers, showing the range of values and quartiles. The box extends from the 25th centile to the 75th centile, with a line at the median (50th centile). Whiskers extend above and below the box to show the highest and lowest values. Statistical analysis performed using a two-tailed t test, n = 5 fluid samples for each group. Concentrations of other metabolites (DHHA, D-2-HG and SSA) were not significantly different as a function of pregnancy status.