Figure 1From: Neurotransmitter alterations in embryonic succinate semialdehyde dehydrogenase (SSADH) deficiency suggest a heightened excitatory state during developmentSchematic of GABA degradation and metabolites accumulating (arrows adjacent to metabolites) in Aldh5a1 deficiency (depicted by cross-hatched box). Abbreviations: SSA, succinate semialdehyde; α-KG, α-ketoglutarate; D-2-HG, D-2-hydroxyglutarate; DHHA, 4,5-dihydroxyhexanoic acid; TCA, tricarboxylic acid.Back to article page