Figure 10

ELP-1 is needed for normal touch sensation. Bars are mean ± s.d. for at least three independent assays of 30–50 animals each. RNAi knockdown of elp-1 in the lin-15b;eri-1 background induces a stronger touch-insensitive phenotype (66 ± 11%, mean ± s.d.) than does partial deletion of elp-1(ok347) (24 ± 5%) and is similar to the defect found in ok347/ozDf1 heterozygotes (82 ± 6%). Percentage of touch-insensitive animals for the remaining genotypes and RNAi treatments are as follows: wild-type (12 ± 0%) and lin-15b;eri-1 without RNAi (19 ± 6%). Tests were conducted blind to genotype or RNAi treatment. *P < 0.001 Fisher's Exact test.