Figure 3
From: The DrosophilaSTIM1 orthologue, dSTIM, has roles in cell fate specification and tissue patterning
Ectopic expression of dSTIM in eye imaginal discs results in small eyes with tetragonal packed ommatidia. Scanning electron micrographs (SEM) of adult eyes in wild-type (wt) flies (A, B) and in flies expressing dSTIMFL(D, E) driven by ey.Gal4. Scale bars in A and D represent 100 μm. Eyes expressing dSTIMFLare smaller than wild-type eyes, and at higher magnification are seen to have a square-shaped ommatidial lattice (E) compared to the hexagonal lattice in wild-type eyes (B). Tangential sections reveal no underlying abnormalities in the specification of photoreceptor clusters (C, F). SEM of adult eyes overexpressing dSTIMFLdriven by GMR.Gal4 (G) and lz.Gal4 (H) show a 'shaven' phenotype in both cases, characterized by loss of interommatidial bristles across most of the eye and mild roughening of the eye surface.