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Figure 4 | BMC Developmental Biology

Figure 4

From: echinus, required for interommatidial cell sorting and cell death in the Drosophila pupal retina, encodes a protein with homology to ubiquitin-specific proteases

Figure 4

Echinus does not require deubiquitinating activity to promote normal IOC death. (A-D) SEMs of adult eyes of various genotypes. (E-H) Pupal retinas of various genotypes stained with anti-Dlg. (A,E) GMR-driven expression of a microRNA targeting ec-SF1 results in an echinus phenotype. (B,F) ecEPΔ4 eyes. (C,G) Eyes of genotype ecEPΔ4; GMR-ec-SF2/+. (D,H) Eyes of genotype ecEPΔ4; GMR-ec-SF3/+. Expression of versions of Echinus that lack essential USP catalytic residues rescues the ecEPΔ4 phenotype.

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BMC Developmental Biology

ISSN: 1471-213X

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