Figure 4

Differentiated enteroendocrine cells have an ability to remain in the cell cycle due to loss of pRb. Intestinal sections from RB^+/+ (A, B, C), RB^+/- (D, E, F) and RB^-/- (G, H, I) newborn mice were stained by immunofluoresence by using anti-Ki67 (Green) (A, D, G) and anti-serotonin (Red) (B, E, H). Merged images with anti-Ki67 (Green), anti-serotonin (Red) and DAPI (Blue) are shown at the bottom (C, F, I).