Figure 4

There was no influence of CDK4 inhibitor on the induction or the maintenance of long-term potentiation in the hippocampal CA1 region. LTP was induced by HFS (100 Hz, 1s). No significant difference was observed between LTP in slices from control (n = 13 slices) and CDK4 inhibitor pretreated slices (n = 11 slices) both at P8-15 (A) and P21-35 (B). Values were presented as a percentage of baseline (mean ± SEM).