Figure 7
From: The chemokine Sdf-1 and its receptor Cxcr4 are required for formation of muscle in zebrafish
Shh signaling represses expression of cxcr4a and sdf1a. Dorsal views (A-P). Ectopic overexpression of shh mRNA (100 pg) and PKI mRNA (100 pg). Embryos between 11–14 h were analyzed. (A-H) Overexpression of shh (A-D) or PKI (E-H) in the somite represses expression of cxcr4a and sdf1a. (I,J; M,N) Control for e12 and id2 transcription by fluorescent-dextran injection. (K,L;O,P) Overexpression of PKI increases transcription of e12 and id2.