Figure 9
Expression of protocadherin17 and 7in the epithelium. A) Protocadherin17 (Pcdh17) expression in the OE is localized to subsets of cells in the neuronal layer (black arrowheads). Expression is also seen in occasional cells in the sustentacular and basal layers. B) Protocadherin7 (Pcdh7) expression in the epithelium is localized to subsets of cells in the neuronal layer (black arrowheads). C) Double-label in situ hybridization using Pcdh17 (green) and Pcdh7 (red) as probes. Although overlap in expression is occasionally observed, most cells express either Pcdh17 (white arrowheads) or Pcdh7 (arrows). D) Double-label in situ hybridization experiment showing domains of expression of Pcdh17 (green) and Pcdh7 (red) in the anterior bulb. The localized expression of Pcdh17 at the VM surface partially overlaps with that of Pcdh7 (domain between arrows) in anterior bulb. Scale bar =25 μm (A,B), 100 μm (C,D).