Figure 8From: Wnt/β-catenin signaling is required for development of the exocrine pancreasWnt signaling regulates exocrine-specific gene expression in cultured pancreatic explants. Immunostaining of e10.5 dorsal pancreatic explants exposed to the Wnt specific inhibitor, PKF 118–310 [20 nM]. Explants were established and then exposed to PKF 118–310 for 7 days. Treatment resulted in decreased expression of amylase, even among PTF1-expressing cells.Back to article page