Figure 9
The dorsal telencephalon has the potential to generate glial restricted progenitor cells independent of ventral cell infiltration. (A-C) Cells with the similar antigenic profile described for the dorsal glial restricted progenitor population were isolated from two day in vitro grown dorsal explants, and can generate GalC+ cells (A) GFAP+ cells (B) but not neurons (C) in mass culture. (D-F) Explant derived putative glial restricted progenitors can generate clones containing GalC+ cells (D) clones containing GFAP+ cells (E) but no clones containing neurons (F) when exposed to the differentiation conditions. (G-I) Split clones of explant derived putative glial restricted progenitor founder cells can generate GalC+ cells (G) GFAP+ cells (H) but not neurons (I). DAPI, blue nuclear stain. Scale bars, 100 μm.