Complex regulation and multiple developmental functions of misfire, the Drosophila melanogasterferlin gene

Table 2 Rescue of the mfr egg patterning defect phenotype by transgenes.

Strain	Female Genotype^†	n*	% Eggs Patterning Defects
control (mfr+)	w/w⁺; bw/SM1; st mfr^Z1386/TM6 or w/w⁺; bw/SM1; st mfr^Z0695/TM6^∞	293	9%
control (mfr-)	w/w⁺; bw/SM1; st mfr^Z1386/st mfr^Z0695	269	40%^Ω
transgenic A	w/w⁺; bw/P{w^+mcmfr^+t10.7}A;mfr^Z1386/mfr^Z0695	197	21%^Ω
transgenic B	w/w⁺; bw/P{w^+mcmfr^+t10.7}B;mfr^Z1386/mfr^Z0695	220	21%^Ω
transgenic A two copies	w; P{w^+mcmfr^+t10.7}A;mfr^Z1386/mfr^Z0695	320	11%

^† A and B are two independent insertions of the transgene
*number of eggs assayed
^∞siblings of the control (mfr-) females that have either the mfr^Z1386or mfr^Z0695mutation balanced over TM6
^Ωpercentage of defects is significantly different from control (mfr+) for control (mfr-)
P < 0.0001 R² = 0.05; for transgenic A, P = 0.0002 R² = 0.04; and for transgenic B, P = 0.0001 R² = 0.04.

ISSN: 1471-213X