Growth curve of lon-8(hu187) mutants. Wild type, lon-1(e185) and lon-8(hu187) animals were synchronized and measured at seven time points. The animals are of indistinguishable length at hatching, but lon-1 and lon-8 animals grow faster than wild type animals throughout larval development and during early adulthood. Later in adult life, lon-1(e185) animals continue to grow at a faster rate (steeper slope angle) than wild type animals, whereas the growth rate of lon-8(hu187) animals stabilizes. At least 100 animals were measured for each strain. a, b, c, for wild type/lon-1 and wild type/lon-8 p < 0.001. d, e for wild type/lon-1, wild type/lon-8 and lon-1/lon-8 p < 0.001. P values were calculated using Student's t-test.