Figure 7

Impaired movement of anterior tailbud cells in N-cad^m117mutants. Posterior (A-C") and anterior (D-G') cells in the tailbud were uncaged at 4 som (A-C,D-G) and imaged at 18 som (B'-C",E'-G'). (A,D) Schematic diagrams of a dorsal view of the tailbud at 4 som, illustrating where the uncaging was done (green dot). (B,C,E-G) Dorsal views of the tailbud at 4 som, showing where the uncaging was done (green label), in WT (B,E) and N-cad^m117mutants (C,F,G). Lateral (B',E') and dorsal (B",E") views of 18som WT embryos indicating the position of uncaged cells (white arrowheads). Lateral (C',F',G') and dorsal (C") views of N-cad^m117mutants indicating position of labeled cells (white arrowheads). Abbreviations and symbols: som, somite; kv, Kupffer's vesicle; asterisk indicates the position of the vacuole in the tailbud, black arrowheads show KV.