Loss of N-cadherin function causes axis shortening. (A-E) Lateral views of live 30 hpf zebrafish embryos imaged with Nomarski optics. Anterior is to the left, dorsal is up. Insets show images of somites at the level of the yolk sac extension. Black arrowheads point to brain defects observed in N-cad mutants. Black arrow points to the characteristic club-shaped, shortened tail in N-cadm117homozygous mutants. WT (A), N-cadp79emcfhomozygous mutant (B), N-cadr2.10homozygous mutant (C), N-cadm117homozygous mutant (D), N-cadm117/p79emcftransheterozygote mutant (E) embryos.