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Table I Genotype frequency of progeny from heterozygote (cubilin exon1–6+/-) matings

From: Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formation

Stage

No. Progeny of Each Genotype

No. Resorbed Embryos

Total No.

Chi-Square p value

 

+/+

+/-

-/-

   

7.5 dpc

7

19

8

0

34

0.767

8.5 dpc

23

29

9

9

70

0.319

9.5 dpc

22

19

7

12

60

0.002

10.5 dpc

15

18

3

1

37

0.018

13.5 dpc

19

17

0

9

45

0.0001

Adult (4 wk)

100

120

0

 

220

0.0001*

  1. Asterisk indicates that the chi-square test was based on a 1:2 ratio of wild-type to heterozygote offspring.