Figure 2
From: Optic cup and facial patterning defects in ocular ectoderm β-catenin gain-of-function mice
Region of Topgal expression in Lens-cre; Catnblox(ex3)mutant embryos. Expression of Topgal in control embryos at the indicated ages either shown in whole-mount (A,B,G,H,M,N) or in section for the eye region (C,I,O). Expression of Topgal in Lens-cre; Catnblox(ex3) embryos at the indicated ages either shown in whole-mount (D,E,J,K,P,Q) or in section for the eye region (F,L,R). The red dashed lines indicate the appropriate regions for comparison between control (B, H) and Topgal; Lens-cre; Catnblox(ex3) embryos. dov-dorsal optic vesicle, ve-ventral ectoderm, wf-whisker follicles, sv-sensory vibrissae, prpe-presumptive retinal epithelium.