Figure 9
From: Hedgehog can drive terminal differentiation of amniote slow skeletal muscle
Murine Hh knockouts have inefficient differentiation and delayed slow myogenesis. A, B. Hindlimbs (A) or forelimbs (B) from E18.5 Ihh-/- or sibling mice were cryo-sectioned and stained for slow (A4.840) and fast (N3.36) MyHC. C. Whole E9.5 Shh-/- or sibling embryos were cryo-sectioned and stained serially for pan (A4.1025) or slow (A4.840) MyHC. Comparable anteroposterior levels are shown, based on the orientation of the heart elsewhere in the sections. s soleus, t tibialis anterior, e extensor digitorum longus, g gastrocnemius, T tibia, F fibula, u ulnar, r radius, A anterior, P posterior, D dorsal, V ventral, L lateral, M medial.