Figure 2
Cleft secondary palate of Wnt1-Cre;Ldb1fl/-mutants. All the samples are E18.5. A,B) Whole mount view of the palate. The nose is toward the top. C-F) Skeleton staining for bone (red) and cartilage (blue). C and D are lateral views of the head. E and F show the palate area after the removal of the lower jaw, in the same orientation as in A and B. Note that the vomer (Vo) and presphenoid (PSp) in F are not visible in E because they are underneath the maxilla (Max) and palatine (PL) normally. Abbreviations: BO, basioccipital; BS, basisphenoid; De, dentary; Fr, frontal bone; LO, lamina obturans; Pa, parietal bone; PMx, premaxilla; Pt, pterygoid. Bar, 1 mm.