Skip to main content

Table 1 Effect of cyclopamine on length of regenerating tail

From: Notochord-derived hedgehog is essential for tail regeneration in Xenopus tadpole

  Day 3 Day 5
Chemicals ET TO CP CP + PM ET TO CP CP + PM
Number 11 11 12 11 9 9 12 10
Mean (μm) 725.3 785.2 401.2 487 1528.8 1751.6 718.4 1168.2
SD 209.3 225.7 171.9 134.1 375.2 408.1 219 293.1
P-value (ET) - 0.26 0.2 E-4 2.4 E-3 - 0.12 2.7 E-6 1.6 E-2
P-value (TO) - - 7.5 E-5 6.1 E-4 - - 2.2 E-7 1.1 E-2
P-value (CP) - - - 0.1 - - - 2.7 E-4
  1. Tail-amputated st. 48 tadpoles were maintained in water containing ethanol (ET, 0.1%), tomatidine (TO, 2.5 μM) or cyclopamine (CP, 2.5 μM) or cyclopamine plus purmorphamine (PM, 0.25 μM). Mean length of the regenerated tails was determined at day 3 and day 5. Student’s t-test was used to identify differences between indicated groups.