Figure 2

Hierarchal cluster analysis of DETs among different stages of development of A. aegypti. The pairwise stages at which differential expression was determined are shown to the right of each self-organizing expression map generated by Cluster 3.0. The stages highlighted in red text indicate the developmental times where the DETS are significantly differentially expressed in A. aegypti. Red and green colors in the heat maps indicate up-regulated (fold-change range: 1.91 to 2.83) and down-regulated genes (fold-change range: -3.21 to - 1.93), respectively. The dark color indicates no significant changes in expression between stages and assumes value zero in the cluster analysis. The cluster trees for expression levels among the developmental stages are shown at the left of the corresponding maps.