Figure 8
From: In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1
Two dimensional hierarchical clustering data identifying mRNAs significantly regulated in PM/PM thyroid. In the two dimensional hierarchical clustering, data from U74 Affymetrix chips identifying mRNAs significantly regulated in E18 PM/PM thyroid in comparison with the wild type are shown. Intensity in the red and green range indicates the increase and decrease in mRNA abundance, respectively. Each row represents a single gene; each column represents a particular experimental sample; each box represents a normalized gene expression value. Hybridization data from U74 Affymetrix chips were normalized using MAS 5.0 software. For each strain, the data represent the mean of three independent samples each composed of the thyroids dissected from four embryos. In PM/PM thyroid, the expression levels of 74 genes were different, with a fold change >2 in comparison with wild type thyroid.