Figure 8

Dose Dependency of Dopamine's Effect on the Migration Velocity of FMB- or HB-NCCs. The graph shows the relationship between Rd/c and each dose of dopamine in the case of FMB-NCC (A) and HB-NCC (B) (*P < 0.05, **P < 0.01; error bars represent ± s.e.m.). The "mean velocity" of FMB-NCCs was increased after dopamine addition at all the concentrations tested (cont: n = 201; 0.01 μM: n = 58, P = 0.038; 0.1 μM: n = 78, P = 3.11E-06; 1 μM: n = 70, P = 0.0362; 10 μM: n = 92, P = 0.00169) (A). The mean velocity of HB-NCCs increased after the addition of dopamine at 0.1 μM (cont: n = 417; 0.01 μM: n = 151, P = 0.445; 0.1 μM: n = 236, P = 0.00353; 1 μM: n = 195, P = 0.288; 10 μM: n = 203, P = 0.11) (B).