Figure 2

Effects of flavopiridol on mouse embryo development in vitro. A. One-cell embryos collected at 20 h phCG were cultured in KSOM medium containing 0, 10, 40, 70, 100, 300, 600, or 1,000 nM flavopiridol, for 84 h. B. Late two-cell- or early four-cell-stage embryos were recovered at 50 h phCG and cultured in KSOM medium without or with 100 nM or 300 nM flavopiridol, for 60 h.