Figure 10

Model for how loss of SRF-dependent adhesion molecules leads to increased proliferation. (A) Adhesion-mediated signaling pathways associated with control of proliferation. SRF regulated molecules are shown in grey boxes. (B) Molecules downregulated by the loss of SRF have been faded and marked by an "X". AJ = adherens junction; FA = focal adhesion; TJ = tight junction (see text for further discussion).