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Figure 2 | BMC Developmental Biology

Figure 2

From: Conditional expression of retrovirally delivered anti-MYCN shRNA as an in vitro model system to study neuronal differentiation in MYCN-amplified neuroblastoma

Figure 2

MYCN knockdown induces neurite outgrowth in MNA neuroblastoma cell lines. MNA Kelly (A) and SK-N-BE(2) (B) cells transiently transfected for 3 days with anti-MYCN (aMN-887 and aMN-1658) and scrambled (Scr control) shRNA expressing plasmids. Cells expressing the aMN shRNAs show neurite outgrowth characteristic of neuronal differentiated cells. White arrows indicate neurite outgrowth.

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