Table 5 Gene expression profiling of wild-type and keaA deficient cells using cDNA microarrays.
From: KeaA, a Dictyostelium kelch-domain protein that regulates the response to stress and development
| Â | Wild type cells | keaA deficient cells |
|---|---|---|
0 h growth × 2 h growth | - | - |
0 h growth × 12 h growth | crystal protein (cryS ) ↑ | crystal protein (cryS ) ↑ |
|  | discoidin I, A chain (dscA ) ↑ | discoidin I, A chain (dscA ) ↑ |
|  | similar to protein kinase C inhibitor (pkiA ) ↑ | - |
|  | 12 kDa protein (csbB ) ↑ | - |
|  | proteosomal alpha subuit 7-1 (prtB , M3R) ↑ | - |
|  | cytochrome c oxidase subunit VI (cxfA ) ↓ | - |
2 h - SNP × 2 h + SNP | penta EF hand calcium binding protein (pefA ) ↑ | - |
|  | culmination specific protein 45 D (culD) ↑ | - |
|  | cisteine protease 4 (cprD, CP4) ↓ | - |
|  | ras GTPase-activating protein ↓ | - |
|  | DG1029 (Ras GAP1) ↓ | - |
|  | G2/M - specific cyclin B (cycB ) ↓ | - |
|  | - | putative calmodulin-binding protein CAM-BP15 (cmbC) ↑ |
|  | - | flavohemoglobin ↑ |
12 h - SNP × 12 h + SNP | culmination specific protein 45 D (culD) ↑ | culmination specific protein 45 D (culD) ↑ |
|  | penta EF hand calcium binding protein (pefA ) ↑ | penta EF hand calcium binding protein (pefA ) ↑ |
|  | calcium-binding protein 1 ↑ | - |
2 h - H 2 O 2 x 2 h H 2 O 2 | glutathione reductase (gsr ) ↑ | - |
|  | major vault protein (mvpB ) ↑ | - |
|  | culmination specific protein 45 D (culD) ↑ | culmination specific protein 45 D (culD) ↑ |
|  | - | calcium-binding protein (CBP2) ↑ |
|  | - | F-box A protein (fbxA ) ↑ |
|  | - | hiwi ↑ |
|  | leucine-rich repeat-containing protein LRR (lrrA ) ↓ | leucine-rich repeat-containing protein LRR (lrrA ) ↓ |
|  | unknow (smlA ) ↓ | - |
|  | cisteine protease 4 (cprD, CP4) ↓ | - |
|  | putative CMF receptor - CMFR1 (cmfB ) ↓ | putative CMF receptor - CMFR1 (cmfB ) ↓ |
|  | major vault protein (mvpA ) ↓ | - |
|  | aquaporin like protein (wacA ) ↓ | - |
|  | G2/M - specific cyclin B (cycB ) ↓ | - |
|  | - | unknown (DG1008, sfbA ) ↓ |
|  | - | sulfite reductase (redA ) ↓ |
12 h - H 2 O 2 x 12 h H 2 O 2 | discoidin I, A chain (dscA ) ↓ | - |
|  | 12 kDa protein (csbB ) ↓ | - |